Matches in SemOpenAlex for { <https://semopenalex.org/work/W1979084502> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W1979084502 endingPage "506" @default.
- W1979084502 startingPage "499" @default.
- W1979084502 abstract "Groups of schoolchildren were immunized with an inactivated recombinant influenza virus vaccine specific for the neuraminidase antigen of Port Chalmers influenza A virus (HeqIN2ch), a conventional biphasic Port Chalmers strain of influenza virus vaccine (H3chN2ch), or a placebo. Immunization with either virus vaccine was found to be safe and had no major adverse effects. Immunization with the Heq1N2ch vaccine resulted in no specific hemagglutination-inhibiting antibody response to H3ch antigen, although a specific neuraminidase antibody response to N2ch antigen was observed in >90% of the vaccinees. A subsequent natural outbreak of influenza virus resulted in serologically proven infection with H3ch virus in 26% of vaccinees receiving H3chN2ch virus vaccine, 47% of those receiving HeqIN2ch virus vaccine, and 44% of those receiving a placebo. However, the protective efficacy against illness was 74.3% for the H3chN2ch vaccine and only 51.4% for the HeqIN2ch vaccine. Regardless of the type of vaccine employed, vaccinees with serologic evidence of infection and clinical illness were found to have very low titers of hemagglutination-inhibiting and neuraminidase antibody. However, vaccinees with serologically proved infection but without clinical illness were found to have titers of antibody to neuraminidase before infection that were four- to eightfold higher than titers in vaccinees who were infected and who had clinical illness." @default.
- W1979084502 created "2016-06-24" @default.
- W1979084502 creator A5000458658 @default.
- W1979084502 creator A5019742164 @default.
- W1979084502 creator A5060762884 @default.
- W1979084502 creator A5066119197 @default.
- W1979084502 creator A5070885444 @default.
- W1979084502 creator A5075623172 @default.
- W1979084502 creator A5083527914 @default.
- W1979084502 date "1977-04-01" @default.
- W1979084502 modified "2023-09-27" @default.
- W1979084502 title "Clinical and Immunologic Evaluation of NeuraminidaseSpecific Influenza A Virus Vaccine in Humans" @default.
- W1979084502 cites W1599799581 @default.
- W1979084502 cites W1665693625 @default.
- W1979084502 cites W1953786867 @default.
- W1979084502 cites W1962612316 @default.
- W1979084502 cites W1984221593 @default.
- W1979084502 cites W2087447110 @default.
- W1979084502 cites W2339538706 @default.
- W1979084502 cites W3022343350 @default.
- W1979084502 doi "https://doi.org/10.1093/infdis/135.4.499" @default.
- W1979084502 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/856917" @default.
- W1979084502 hasPublicationYear "1977" @default.
- W1979084502 type Work @default.
- W1979084502 sameAs 1979084502 @default.
- W1979084502 citedByCount "58" @default.
- W1979084502 countsByYear W19790845022012 @default.
- W1979084502 countsByYear W19790845022013 @default.
- W1979084502 countsByYear W19790845022014 @default.
- W1979084502 countsByYear W19790845022015 @default.
- W1979084502 countsByYear W19790845022016 @default.
- W1979084502 countsByYear W19790845022018 @default.
- W1979084502 countsByYear W19790845022019 @default.
- W1979084502 countsByYear W19790845022020 @default.
- W1979084502 countsByYear W19790845022021 @default.
- W1979084502 crossrefType "journal-article" @default.
- W1979084502 hasAuthorship W1979084502A5000458658 @default.
- W1979084502 hasAuthorship W1979084502A5019742164 @default.
- W1979084502 hasAuthorship W1979084502A5060762884 @default.
- W1979084502 hasAuthorship W1979084502A5066119197 @default.
- W1979084502 hasAuthorship W1979084502A5070885444 @default.
- W1979084502 hasAuthorship W1979084502A5075623172 @default.
- W1979084502 hasAuthorship W1979084502A5083527914 @default.
- W1979084502 hasConcept C134164806 @default.
- W1979084502 hasConcept C147483822 @default.
- W1979084502 hasConcept C159047783 @default.
- W1979084502 hasConcept C159654299 @default.
- W1979084502 hasConcept C182072434 @default.
- W1979084502 hasConcept C203014093 @default.
- W1979084502 hasConcept C22070199 @default.
- W1979084502 hasConcept C22889606 @default.
- W1979084502 hasConcept C2522874641 @default.
- W1979084502 hasConcept C2780689484 @default.
- W1979084502 hasConcept C2780801004 @default.
- W1979084502 hasConcept C32611913 @default.
- W1979084502 hasConcept C45189115 @default.
- W1979084502 hasConcept C71924100 @default.
- W1979084502 hasConceptScore W1979084502C134164806 @default.
- W1979084502 hasConceptScore W1979084502C147483822 @default.
- W1979084502 hasConceptScore W1979084502C159047783 @default.
- W1979084502 hasConceptScore W1979084502C159654299 @default.
- W1979084502 hasConceptScore W1979084502C182072434 @default.
- W1979084502 hasConceptScore W1979084502C203014093 @default.
- W1979084502 hasConceptScore W1979084502C22070199 @default.
- W1979084502 hasConceptScore W1979084502C22889606 @default.
- W1979084502 hasConceptScore W1979084502C2522874641 @default.
- W1979084502 hasConceptScore W1979084502C2780689484 @default.
- W1979084502 hasConceptScore W1979084502C2780801004 @default.
- W1979084502 hasConceptScore W1979084502C32611913 @default.
- W1979084502 hasConceptScore W1979084502C45189115 @default.
- W1979084502 hasConceptScore W1979084502C71924100 @default.
- W1979084502 hasIssue "4" @default.
- W1979084502 hasLocation W19790845021 @default.
- W1979084502 hasLocation W19790845022 @default.
- W1979084502 hasOpenAccess W1979084502 @default.
- W1979084502 hasPrimaryLocation W19790845021 @default.
- W1979084502 hasRelatedWork W1908731892 @default.
- W1979084502 hasRelatedWork W2038899530 @default.
- W1979084502 hasRelatedWork W2081709747 @default.
- W1979084502 hasRelatedWork W2094360815 @default.
- W1979084502 hasRelatedWork W2132204826 @default.
- W1979084502 hasRelatedWork W2164759517 @default.
- W1979084502 hasRelatedWork W2350366197 @default.
- W1979084502 hasRelatedWork W2358831769 @default.
- W1979084502 hasRelatedWork W2423096141 @default.
- W1979084502 hasRelatedWork W2781624698 @default.
- W1979084502 hasVolume "135" @default.
- W1979084502 isParatext "false" @default.
- W1979084502 isRetracted "false" @default.
- W1979084502 magId "1979084502" @default.
- W1979084502 workType "article" @default.