FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1979137262> ?p ?o ?g. }

• W1979137262 endingPage "324" @default.
• W1979137262 startingPage "319" @default.
• W1979137262 abstract "1. To test whether cystic fibrosis (CF) altered the kinetics and dynamics of oral salbutamol, 11 patients with CF (19-33 years old; five females; FEV1: 37 +/- 12% of predicted value) and 10 healthy volunteers (20-41 years old; five females; FEV1: 99 +/- 14% of predicted value) received orally 4 mg salbutamol. 2. The estimated pharmacokinetic parameters of salbutamol in patients with CF were identical to those in healthy subjects. For instance, peak plasma concentrations of salbutamol were 10.5 +/- 2.6 (mean +/- s.d.) and 10.2 +/- 2.9 ng ml-1 (NS), and the area under salbutamol plasma concentrations as a function of time (AUC (0, 7 h)) was 43.0 +/- 9.3 ng ml-1 h and 43.3 +/- 12.7 ng ml-1 h (NS) in CF patients and in healthy subjects, respectively. Since on a mg kg-1 dose basis, CF patients received a dose 28% greater than healthy subjects, this lack of differences implies a decrease in the amount of salbutamol absorbed, or alternatively, an increase in both clearance and volume of distribution of salbutamol. 3. Salbutamol did not elicit bronchodilation in CF patients, but increased heart rate from 77 +/- 2 to 103 +/- 3 beats min-1 (P < 0.05). 4. Salbutamol decreased plasma potassium concentrations from 4.5 +/- 0.1 to 3.8 +/- 0.1 mmol l-1 in the CF group (P < 0.05) and from 4.1 +/- 0.2 to 3.4 +/- 0.1 mmol l-1 in the controls (P < 0.05).(ABSTRACT TRUNCATED AT 250 WORDS)" @default.
• W1979137262 created "2016-06-24" @default.
• W1979137262 creator A5011191119 @default.
• W1979137262 creator A5082507673 @default.
• W1979137262 creator A5083600483 @default.
• W1979137262 creator A5086748264 @default.
• W1979137262 creator A5090099112 @default.
• W1979137262 date "1995-10-01" @default.
• W1979137262 modified "2023-10-02" @default.
• W1979137262 title "Plasma concentrations and effects of salbutamol administered orally to patients with cystic fibrosis." @default.
• W1979137262 cites W123831112 @default.
• W1979137262 cites W1565534226 @default.
• W1979137262 cites W1588925236 @default.
• W1979137262 cites W1589844850 @default.
• W1979137262 cites W1632390614 @default.
• W1979137262 cites W1679419763 @default.
• W1979137262 cites W1860955989 @default.
• W1979137262 cites W1900515148 @default.
• W1979137262 cites W1932396143 @default.
• W1979137262 cites W1975588459 @default.
• W1979137262 cites W1977984023 @default.
• W1979137262 cites W1980356749 @default.
• W1979137262 cites W1998268059 @default.
• W1979137262 cites W2005815716 @default.
• W1979137262 cites W2006323889 @default.
• W1979137262 cites W2006931745 @default.
• W1979137262 cites W2011285804 @default.
• W1979137262 cites W2012400732 @default.
• W1979137262 cites W2019186425 @default.
• W1979137262 cites W2026314784 @default.
• W1979137262 cites W2043224247 @default.
• W1979137262 cites W2062114031 @default.
• W1979137262 cites W2065242414 @default.
• W1979137262 cites W2085229284 @default.
• W1979137262 cites W2086438135 @default.
• W1979137262 cites W2089995900 @default.
• W1979137262 cites W2092364880 @default.
• W1979137262 cites W2094261352 @default.
• W1979137262 cites W2100013950 @default.
• W1979137262 cites W2101228796 @default.
• W1979137262 cites W2105182850 @default.
• W1979137262 cites W2115112672 @default.
• W1979137262 cites W2129993729 @default.
• W1979137262 cites W2138672075 @default.
• W1979137262 cites W2147665357 @default.
• W1979137262 cites W2147839947 @default.
• W1979137262 cites W2282715653 @default.
• W1979137262 cites W2326141513 @default.
• W1979137262 cites W2419100232 @default.
• W1979137262 cites W4206781879 @default.
• W1979137262 cites W4210288420 @default.
• W1979137262 cites W65304036 @default.
• W1979137262 doi "https://doi.org/10.1111/j.1365-2125.1995.tb04553.x" @default.
• W1979137262 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1365150" @default.
• W1979137262 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8554933" @default.
• W1979137262 hasPublicationYear "1995" @default.
• W1979137262 type Work @default.
• W1979137262 sameAs 1979137262 @default.
• W1979137262 citedByCount "0" @default.
• W1979137262 crossrefType "journal-article" @default.
• W1979137262 hasAuthorship W1979137262A5011191119 @default.
• W1979137262 hasAuthorship W1979137262A5082507673 @default.
• W1979137262 hasAuthorship W1979137262A5083600483 @default.
• W1979137262 hasAuthorship W1979137262A5086748264 @default.
• W1979137262 hasAuthorship W1979137262A5090099112 @default.
• W1979137262 hasBestOaLocation W19791372622 @default.
• W1979137262 hasConcept C112705442 @default.
• W1979137262 hasConcept C126322002 @default.
• W1979137262 hasConcept C134018914 @default.
• W1979137262 hasConcept C139254425 @default.
• W1979137262 hasConcept C2776042228 @default.
• W1979137262 hasConcept C2776938444 @default.
• W1979137262 hasConcept C2777394947 @default.
• W1979137262 hasConcept C2781018748 @default.
• W1979137262 hasConcept C42219234 @default.
• W1979137262 hasConcept C71924100 @default.
• W1979137262 hasConceptScore W1979137262C112705442 @default.
• W1979137262 hasConceptScore W1979137262C126322002 @default.
• W1979137262 hasConceptScore W1979137262C134018914 @default.
• W1979137262 hasConceptScore W1979137262C139254425 @default.
• W1979137262 hasConceptScore W1979137262C2776042228 @default.
• W1979137262 hasConceptScore W1979137262C2776938444 @default.
• W1979137262 hasConceptScore W1979137262C2777394947 @default.
• W1979137262 hasConceptScore W1979137262C2781018748 @default.
• W1979137262 hasConceptScore W1979137262C42219234 @default.
• W1979137262 hasConceptScore W1979137262C71924100 @default.
• W1979137262 hasIssue "4" @default.
• W1979137262 hasLocation W19791372621 @default.
• W1979137262 hasLocation W19791372622 @default.
• W1979137262 hasLocation W19791372623 @default.
• W1979137262 hasLocation W19791372624 @default.
• W1979137262 hasOpenAccess W1979137262 @default.
• W1979137262 hasPrimaryLocation W19791372621 @default.
• W1979137262 hasRelatedWork W1572696483 @default.
• W1979137262 hasRelatedWork W1976668668 @default.
• W1979137262 hasRelatedWork W1978954584 @default.
• W1979137262 hasRelatedWork W2023850928 @default.
• W1979137262 hasRelatedWork W2030593141 @default.

• next