FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1979195429> ?p ?o ?g. }

• W1979195429 endingPage "505" @default.
• W1979195429 startingPage "501" @default.
• W1979195429 abstract "Elongation factor G (EF-G) from Escherichia coli is a large, five-domain GTPase that promotes tRNA translocation on the ribosome. Full activity requires GTP hydrolysis, suggesting that a conformational change of the factor is important for function. To restrict the intramolecular mobility, two cysteine residues were engineered into domains 1 and 5 of EF-G that spontaneously formed a disulfide cross-link. Cross-linked EF-G retained GTPase activity on the ribosome, whereas it was inactive in translocation as well as in turnover. Both activities were restored when the cross-link was reversed by reduction. These results strongly argue against a GTPase switch-type model of EF-G function and demonstrate that conformational mobility is an absolute requirement for EF-G function on the ribosome." @default.
• W1979195429 created "2016-06-24" @default.
• W1979195429 creator A5017069360 @default.
• W1979195429 creator A5028476493 @default.
• W1979195429 creator A5046922361 @default.
• W1979195429 creator A5051136232 @default.
• W1979195429 creator A5091287470 @default.
• W1979195429 date "2000-08-01" @default.
• W1979195429 modified "2023-09-29" @default.
• W1979195429 title "Conformationally Restricted Elongation Factor G Retains GTPase Activity but Is Inactive in Translocation on the Ribosome" @default.
• W1979195429 cites W1486369891 @default.
• W1979195429 cites W1607300871 @default.
• W1979195429 cites W1810161475 @default.
• W1979195429 cites W1844993037 @default.
• W1979195429 cites W1977087022 @default.
• W1979195429 cites W1979048982 @default.
• W1979195429 cites W1984242761 @default.
• W1979195429 cites W1984294833 @default.
• W1979195429 cites W2001284253 @default.
• W1979195429 cites W2022895983 @default.
• W1979195429 cites W2031225710 @default.
• W1979195429 cites W2034304629 @default.
• W1979195429 cites W2050861719 @default.
• W1979195429 cites W2059158991 @default.
• W1979195429 cites W2059390568 @default.
• W1979195429 cites W2068496672 @default.
• W1979195429 cites W2069885328 @default.
• W1979195429 cites W2080354455 @default.
• W1979195429 cites W2152348402 @default.
• W1979195429 cites W2434139104 @default.
• W1979195429 doi "https://doi.org/10.1016/s1097-2765(00)00049-6" @default.
• W1979195429 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10983996" @default.
• W1979195429 hasPublicationYear "2000" @default.
• W1979195429 type Work @default.
• W1979195429 sameAs 1979195429 @default.
• W1979195429 citedByCount "62" @default.
• W1979195429 countsByYear W19791954292012 @default.
• W1979195429 countsByYear W19791954292013 @default.
• W1979195429 countsByYear W19791954292014 @default.
• W1979195429 countsByYear W19791954292015 @default.
• W1979195429 countsByYear W19791954292016 @default.
• W1979195429 countsByYear W19791954292017 @default.
• W1979195429 countsByYear W19791954292019 @default.
• W1979195429 countsByYear W19791954292021 @default.
• W1979195429 countsByYear W19791954292022 @default.
• W1979195429 crossrefType "journal-article" @default.
• W1979195429 hasAuthorship W1979195429A5017069360 @default.
• W1979195429 hasAuthorship W1979195429A5028476493 @default.
• W1979195429 hasAuthorship W1979195429A5046922361 @default.
• W1979195429 hasAuthorship W1979195429A5051136232 @default.
• W1979195429 hasAuthorship W1979195429A5091287470 @default.
• W1979195429 hasBestOaLocation W19791954291 @default.
• W1979195429 hasConcept C104317684 @default.
• W1979195429 hasConcept C105580179 @default.
• W1979195429 hasConcept C112950240 @default.
• W1979195429 hasConcept C118716 @default.
• W1979195429 hasConcept C12554922 @default.
• W1979195429 hasConcept C138626823 @default.
• W1979195429 hasConcept C139124968 @default.
• W1979195429 hasConcept C149364088 @default.
• W1979195429 hasConcept C181199279 @default.
• W1979195429 hasConcept C185592680 @default.
• W1979195429 hasConcept C191897082 @default.
• W1979195429 hasConcept C192562407 @default.
• W1979195429 hasConcept C207332259 @default.
• W1979195429 hasConcept C2777339483 @default.
• W1979195429 hasConcept C33947775 @default.
• W1979195429 hasConcept C55493867 @default.
• W1979195429 hasConcept C67705224 @default.
• W1979195429 hasConcept C71240020 @default.
• W1979195429 hasConcept C75079739 @default.
• W1979195429 hasConcept C75442077 @default.
• W1979195429 hasConcept C86803240 @default.
• W1979195429 hasConcept C88478588 @default.
• W1979195429 hasConcept C95444343 @default.
• W1979195429 hasConceptScore W1979195429C104317684 @default.
• W1979195429 hasConceptScore W1979195429C105580179 @default.
• W1979195429 hasConceptScore W1979195429C112950240 @default.
• W1979195429 hasConceptScore W1979195429C118716 @default.
• W1979195429 hasConceptScore W1979195429C12554922 @default.
• W1979195429 hasConceptScore W1979195429C138626823 @default.
• W1979195429 hasConceptScore W1979195429C139124968 @default.
• W1979195429 hasConceptScore W1979195429C149364088 @default.
• W1979195429 hasConceptScore W1979195429C181199279 @default.
• W1979195429 hasConceptScore W1979195429C185592680 @default.
• W1979195429 hasConceptScore W1979195429C191897082 @default.
• W1979195429 hasConceptScore W1979195429C192562407 @default.
• W1979195429 hasConceptScore W1979195429C207332259 @default.
• W1979195429 hasConceptScore W1979195429C2777339483 @default.
• W1979195429 hasConceptScore W1979195429C33947775 @default.
• W1979195429 hasConceptScore W1979195429C55493867 @default.
• W1979195429 hasConceptScore W1979195429C67705224 @default.
• W1979195429 hasConceptScore W1979195429C71240020 @default.
• W1979195429 hasConceptScore W1979195429C75079739 @default.
• W1979195429 hasConceptScore W1979195429C75442077 @default.
• W1979195429 hasConceptScore W1979195429C86803240 @default.
• W1979195429 hasConceptScore W1979195429C88478588 @default.
• W1979195429 hasConceptScore W1979195429C95444343 @default.

• next