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• W1979224746 abstract "Carbosilane dendrimers bearing galabiose (Galα1–4Gal) with three, four, and six galabiose units at the periphery of the dendrimers were synthesized for use as artificial inhibitors against Shiga toxins (Stxs) produced by Escherichia coli O157:H7. The galabiose unit, prepared from penta-O-acetyl-β-d-galactopyranose, was linked with carbosilane dendrimers of three shapes to afford acetyl-protected glycodendrimers in good yields. De-O-acetylation of the clusters was carried out in the presence of NaOMe and then aq NaOH to give the desired three shapes of galabiose-coated carbosilane dendrimers. Their biological activities toward Stxs were evaluated by kinetic analysis, binding assays, and cytotoxic assays." @default.
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• W1979224746 date "2006-05-01" @default.
• W1979224746 modified "2023-10-15" @default.
• W1979224746 title "Syntheses and Vero toxin-binding activities of carbosilane dendrimers periphery-functionalized with galabiose" @default.
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• W1979224746 doi "https://doi.org/10.1016/j.tet.2006.03.042" @default.
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