Matches in SemOpenAlex for { <https://semopenalex.org/work/W1979253405> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W1979253405 abstract "The effects of K+ channel modulators, tetraethylammonium, 4-aminopyridine and diazoxide, and high extracellular K+ on cell growth and agonist-induced intracellular Ca2+ mobilization were investigated. Two human brain tumour cell lines, U-373 MG astrocytoma and SK-N-MC neuroblastoma, were used as model cellular systems. K+ channel modulators and increased extracellular K+ concentration inhibited tumour cell growth in a dose-related fashion in both cell lines. In addition, agonist (carbachol or serum)-induced intracellular Ca2+ mobilization was also blocked by the pretreatment of growth-inhibitory concentrations of K+ channel modulators and high extracellular K+. Thus, these results suggest that K+ channel modulators are effective inhibitors of brain tumour cell growth and that their growth regulation may be due to the interference with the intracellular Ca2+ signalling mechanisms." @default.
- W1979253405 created "2016-06-24" @default.
- W1979253405 creator A5055975685 @default.
- W1979253405 creator A5075027403 @default.
- W1979253405 creator A5086997980 @default.
- W1979253405 date "1993-11-01" @default.
- W1979253405 modified "2023-09-26" @default.
- W1979253405 title "Inhibition of cell growth by K+ channel modulators is due to interference with agonist-induced Ca2+ release" @default.
- W1979253405 cites W1507990006 @default.
- W1979253405 cites W1546078475 @default.
- W1979253405 cites W1974032258 @default.
- W1979253405 cites W1989611513 @default.
- W1979253405 cites W1998852147 @default.
- W1979253405 cites W2004947583 @default.
- W1979253405 cites W2005291650 @default.
- W1979253405 cites W2039857269 @default.
- W1979253405 cites W2081160680 @default.
- W1979253405 cites W2081653633 @default.
- W1979253405 cites W2085099577 @default.
- W1979253405 cites W2105994616 @default.
- W1979253405 cites W2111766710 @default.
- W1979253405 cites W2122408922 @default.
- W1979253405 cites W2141260882 @default.
- W1979253405 cites W2141829216 @default.
- W1979253405 cites W2165527434 @default.
- W1979253405 cites W2268145670 @default.
- W1979253405 doi "https://doi.org/10.1016/0898-6568(93)90041-j" @default.
- W1979253405 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8130083" @default.
- W1979253405 hasPublicationYear "1993" @default.
- W1979253405 type Work @default.
- W1979253405 sameAs 1979253405 @default.
- W1979253405 citedByCount "28" @default.
- W1979253405 countsByYear W19792534052014 @default.
- W1979253405 countsByYear W19792534052015 @default.
- W1979253405 countsByYear W19792534052020 @default.
- W1979253405 countsByYear W19792534052022 @default.
- W1979253405 crossrefType "journal-article" @default.
- W1979253405 hasAuthorship W1979253405A5055975685 @default.
- W1979253405 hasAuthorship W1979253405A5075027403 @default.
- W1979253405 hasAuthorship W1979253405A5086997980 @default.
- W1979253405 hasConcept C12554922 @default.
- W1979253405 hasConcept C153461711 @default.
- W1979253405 hasConcept C170493617 @default.
- W1979253405 hasConcept C178790620 @default.
- W1979253405 hasConcept C185592680 @default.
- W1979253405 hasConcept C2778938600 @default.
- W1979253405 hasConcept C2778988552 @default.
- W1979253405 hasConcept C2781295685 @default.
- W1979253405 hasConcept C28406088 @default.
- W1979253405 hasConcept C517785266 @default.
- W1979253405 hasConcept C519063684 @default.
- W1979253405 hasConcept C54355233 @default.
- W1979253405 hasConcept C55493867 @default.
- W1979253405 hasConcept C62112901 @default.
- W1979253405 hasConcept C79879829 @default.
- W1979253405 hasConcept C81885089 @default.
- W1979253405 hasConcept C83743174 @default.
- W1979253405 hasConcept C86803240 @default.
- W1979253405 hasConcept C95444343 @default.
- W1979253405 hasConceptScore W1979253405C12554922 @default.
- W1979253405 hasConceptScore W1979253405C153461711 @default.
- W1979253405 hasConceptScore W1979253405C170493617 @default.
- W1979253405 hasConceptScore W1979253405C178790620 @default.
- W1979253405 hasConceptScore W1979253405C185592680 @default.
- W1979253405 hasConceptScore W1979253405C2778938600 @default.
- W1979253405 hasConceptScore W1979253405C2778988552 @default.
- W1979253405 hasConceptScore W1979253405C2781295685 @default.
- W1979253405 hasConceptScore W1979253405C28406088 @default.
- W1979253405 hasConceptScore W1979253405C517785266 @default.
- W1979253405 hasConceptScore W1979253405C519063684 @default.
- W1979253405 hasConceptScore W1979253405C54355233 @default.
- W1979253405 hasConceptScore W1979253405C55493867 @default.
- W1979253405 hasConceptScore W1979253405C62112901 @default.
- W1979253405 hasConceptScore W1979253405C79879829 @default.
- W1979253405 hasConceptScore W1979253405C81885089 @default.
- W1979253405 hasConceptScore W1979253405C83743174 @default.
- W1979253405 hasConceptScore W1979253405C86803240 @default.
- W1979253405 hasConceptScore W1979253405C95444343 @default.
- W1979253405 hasLocation W19792534051 @default.
- W1979253405 hasLocation W19792534052 @default.
- W1979253405 hasOpenAccess W1979253405 @default.
- W1979253405 hasPrimaryLocation W19792534051 @default.
- W1979253405 hasRelatedWork W1490783082 @default.
- W1979253405 hasRelatedWork W1552536758 @default.
- W1979253405 hasRelatedWork W1979253405 @default.
- W1979253405 hasRelatedWork W2017198821 @default.
- W1979253405 hasRelatedWork W2034896017 @default.
- W1979253405 hasRelatedWork W2076520096 @default.
- W1979253405 hasRelatedWork W2130294388 @default.
- W1979253405 hasRelatedWork W2255784148 @default.
- W1979253405 hasRelatedWork W2395183976 @default.
- W1979253405 hasRelatedWork W52810583 @default.
- W1979253405 isParatext "false" @default.
- W1979253405 isRetracted "false" @default.
- W1979253405 magId "1979253405" @default.
- W1979253405 workType "article" @default.