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- W1979280866 abstract "The biopsies of normal lumbar and dorsal thoracic pig epidermis and dermis are described ultrastructurally at one, three, five, seven, nine and fourteen weeks and compared to the human integument. In the epidermis, basal cell projections extended into the dermis and increased slightly with age. Intraepidermal axons were seen. The basal lamina thickened opposite the hemidesmosomes of the epidermal-dermal junction. Small anchoring fibrils extended from the basal lamina into the dermis. Mitochondria were concentrated beneath the cellular nuclei of the stratum basale. Upper stratum spinosum and stratum granulosum cells contained membrane coating granules. The stratum corneum contained cells of varying density. The only intraepidermal nonkeratinocytes observed were melanocytes and Langerhans-like cells. Both were similar to those of humans. In the dermis, the interfollicular muscle resembled the arrector pili and smooth muscle found in other body areas. Nerve fibers were similar to those described in humans except subepidermal nerve endings contained mitochondria. One unexpected finding was the presence of mast cells which were enveloped by a zone of loose floccular material which stained positive with PAS from seven through fourteen weeks of age. Mast cell population density peaked at seven weeks and was greater in the papillary dermis than in the reticular dermis. Generally, the pig integument is morphologically similar to that of man and would serve as a useful animal model when age changes are accounted for." @default.
- W1979280866 created "2016-06-24" @default.
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- W1979280866 date "1985-06-01" @default.
- W1979280866 modified "2023-09-27" @default.
- W1979280866 title "Ultrastructure of the Integument of the Domestic Pig (Sus scroh) from One through Fourteen Weeks of Age" @default.
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- W1979280866 doi "https://doi.org/10.1111/j.1439-0264.1985.tb00270.x" @default.
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