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- W1979321729 abstract "Cardiac surgery involving a cardiopulmonary bypass is associated with the activation of the hemostatic/inflammatory system. This is caused by the contact of blood with large nonendothelial surfaces, operative trauma, the suction and reinfusion of tissue-factor enriched blood from the operation field, and the release of cytokines from the ischemic tissue. 1 Asimakopoulos G. Systemic inflammtion and cardiac surgery an update. Perfusion. 2001; 16: 353-360 Crossref PubMed Scopus (149) Google Scholar As a result, platelets and coagulation factors are progressively consumed and the systemic inflammatory response is stimulated. This increases the risk of hemorrhage (with a subsequent need for a transfusion), leading to an increased risk of infections and organ failure." @default.
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- W1979321729 date "2003-02-01" @default.
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- W1979321729 title "Effects of tirofiban on hemostatic activation and inflammatory response during cardiopulmonary bypass" @default.
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- W1979321729 doi "https://doi.org/10.1016/s0002-9149(02)03167-3" @default.
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