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- W1979347978 abstract "The human ACP1 locus encodes a genetically polymorphic cytoplasmic low-molecular-weight acid phosphatase. Each of the common alleles encodes two isoforms, f and s. Both isozymes are of equal length (157 residues) but differ in sequence over an internal 34 residue segment. Substantial portions of the ACP1*A, *B and *C alleles common to Europeans have been sequenced. Six linearly positioned exons containing codons 14 to 157 were identified. Two exons of equal length (114bp) interspaced by a short (41bp), probably nonfunctional, intron encode the specific f and s segments, respectively. These findings strongly support an alternative RNA splicing hypothesis. In addition, three allele-specific base substitutions were encountered." @default.
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- W1979347978 date "1993-10-01" @default.
- W1979347978 modified "2023-09-26" @default.
- W1979347978 title "Exon Structure at the Human ACP1 Locus Supports Alternative Splicing Model for f-Isozyme and s-Isozyme Generation" @default.
- W1979347978 doi "https://doi.org/10.1006/bbrc.1993.2269" @default.
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