Matches in SemOpenAlex for { <https://semopenalex.org/work/W1979371446> ?p ?o ?g. }
- W1979371446 endingPage "66" @default.
- W1979371446 startingPage "59" @default.
- W1979371446 abstract "In this study, ultra-performance liquid chromatography (UPLC)/quadrupole-time-of-flight mass spectrometry (QTOF-MS) was applied to the rapid analysis of 20(S)-protopanaxadiol (PPD) metabolites in rats after oral administration, enabling the structural characterization of 23 metabolites in plasma, bile, urine, and feces. 16 of these, including M1-M5, M9, and M11-M15, have not been previously reported. The results also indicated that demethylation, dehydration, dehydrogenation, oxidation, deoxidation, and glucuronidation were the major metabolic reactions of PPD in vivo. This study provides important information about the metabolism of PPD which will be helpful for fully understanding its mechanism of action. Furthermore, structural modification of PPD in vivo may aid in obtaining new chemical derivatives for pharmacological screening." @default.
- W1979371446 created "2016-06-24" @default.
- W1979371446 creator A5008637608 @default.
- W1979371446 creator A5015126339 @default.
- W1979371446 creator A5035774966 @default.
- W1979371446 creator A5049539908 @default.
- W1979371446 creator A5058638624 @default.
- W1979371446 creator A5060173991 @default.
- W1979371446 creator A5068108543 @default.
- W1979371446 date "2013-08-01" @default.
- W1979371446 modified "2023-10-02" @default.
- W1979371446 title "Characterization of metabolites of 20(S)-protopanaxadiol in rats using ultra-performance liquid chromatography/quadrupole-time-of-flight mass spectrometry" @default.
- W1979371446 cites W1968471719 @default.
- W1979371446 cites W1974476408 @default.
- W1979371446 cites W1982638378 @default.
- W1979371446 cites W1982861638 @default.
- W1979371446 cites W1989422881 @default.
- W1979371446 cites W1993944073 @default.
- W1979371446 cites W1996526487 @default.
- W1979371446 cites W2009537627 @default.
- W1979371446 cites W2011592270 @default.
- W1979371446 cites W2020543511 @default.
- W1979371446 cites W2033141431 @default.
- W1979371446 cites W2041080192 @default.
- W1979371446 cites W2043175504 @default.
- W1979371446 cites W2055048861 @default.
- W1979371446 cites W2068396287 @default.
- W1979371446 cites W2073023013 @default.
- W1979371446 cites W2078335383 @default.
- W1979371446 cites W2083000346 @default.
- W1979371446 cites W2083664910 @default.
- W1979371446 cites W2084104895 @default.
- W1979371446 cites W2092725953 @default.
- W1979371446 cites W2114850456 @default.
- W1979371446 cites W2118977816 @default.
- W1979371446 doi "https://doi.org/10.1016/j.jchromb.2013.03.028" @default.
- W1979371446 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23877070" @default.
- W1979371446 hasPublicationYear "2013" @default.
- W1979371446 type Work @default.
- W1979371446 sameAs 1979371446 @default.
- W1979371446 citedByCount "12" @default.
- W1979371446 countsByYear W19793714462013 @default.
- W1979371446 countsByYear W19793714462014 @default.
- W1979371446 countsByYear W19793714462015 @default.
- W1979371446 countsByYear W19793714462016 @default.
- W1979371446 countsByYear W19793714462017 @default.
- W1979371446 countsByYear W19793714462018 @default.
- W1979371446 countsByYear W19793714462019 @default.
- W1979371446 countsByYear W19793714462023 @default.
- W1979371446 crossrefType "journal-article" @default.
- W1979371446 hasAuthorship W1979371446A5008637608 @default.
- W1979371446 hasAuthorship W1979371446A5015126339 @default.
- W1979371446 hasAuthorship W1979371446A5035774966 @default.
- W1979371446 hasAuthorship W1979371446A5049539908 @default.
- W1979371446 hasAuthorship W1979371446A5058638624 @default.
- W1979371446 hasAuthorship W1979371446A5060173991 @default.
- W1979371446 hasAuthorship W1979371446A5068108543 @default.
- W1979371446 hasConcept C104317684 @default.
- W1979371446 hasConcept C142724271 @default.
- W1979371446 hasConcept C150194340 @default.
- W1979371446 hasConcept C150903083 @default.
- W1979371446 hasConcept C162356407 @default.
- W1979371446 hasConcept C179998833 @default.
- W1979371446 hasConcept C185592680 @default.
- W1979371446 hasConcept C190727270 @default.
- W1979371446 hasConcept C192989942 @default.
- W1979371446 hasConcept C202199734 @default.
- W1979371446 hasConcept C202751555 @default.
- W1979371446 hasConcept C204787440 @default.
- W1979371446 hasConcept C207001950 @default.
- W1979371446 hasConcept C2776539398 @default.
- W1979371446 hasConcept C2777032962 @default.
- W1979371446 hasConcept C2777477808 @default.
- W1979371446 hasConcept C2779232237 @default.
- W1979371446 hasConcept C2779907587 @default.
- W1979371446 hasConcept C2780026642 @default.
- W1979371446 hasConcept C3019798703 @default.
- W1979371446 hasConcept C31827203 @default.
- W1979371446 hasConcept C43617362 @default.
- W1979371446 hasConcept C55493867 @default.
- W1979371446 hasConcept C62231903 @default.
- W1979371446 hasConcept C71924100 @default.
- W1979371446 hasConcept C86803240 @default.
- W1979371446 hasConcept C87644729 @default.
- W1979371446 hasConceptScore W1979371446C104317684 @default.
- W1979371446 hasConceptScore W1979371446C142724271 @default.
- W1979371446 hasConceptScore W1979371446C150194340 @default.
- W1979371446 hasConceptScore W1979371446C150903083 @default.
- W1979371446 hasConceptScore W1979371446C162356407 @default.
- W1979371446 hasConceptScore W1979371446C179998833 @default.
- W1979371446 hasConceptScore W1979371446C185592680 @default.
- W1979371446 hasConceptScore W1979371446C190727270 @default.
- W1979371446 hasConceptScore W1979371446C192989942 @default.
- W1979371446 hasConceptScore W1979371446C202199734 @default.
- W1979371446 hasConceptScore W1979371446C202751555 @default.
- W1979371446 hasConceptScore W1979371446C204787440 @default.
- W1979371446 hasConceptScore W1979371446C207001950 @default.
- W1979371446 hasConceptScore W1979371446C2776539398 @default.