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- W1979379788 abstract "Twelve out of 15 patients (9 males and 6 females) with laboratory-proven fungal keratitis were treated with topical clotrimazole, a synthetic imidazole derivative. Their ages ranged from 8 to 70 years. The posttreatment visual acuities were significantly better than the pretreatment visual acuities. No significant biomicroscopic signs of ocular surface toxicity were noted. The ocular condition in 3 patients (all infected with Fusarium solani) deteriorated to blindness despite the antifungal therapy.The clotrimazole usually marketed as dermatological preparation can be used in a diluted form to treat human keratomycosis safely and successfully. A combination with a polyene derivative should be considered in the treatment of fungal corneal infection due to Fusarium spp." @default.
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- W1979379788 date "2001-01-01" @default.
- W1979379788 modified "2023-09-27" @default.
- W1979379788 title "Use of Topical Clotrimazole in Human Keratomycosis" @default.
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- W1979379788 doi "https://doi.org/10.1159/000050885" @default.
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