Matches in SemOpenAlex for { <https://semopenalex.org/work/W1979409715> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W1979409715 endingPage "237" @default.
- W1979409715 startingPage "231" @default.
- W1979409715 abstract "The effects of sodium valporate on extracellularly recorded spontaneous neuronal activity and its interaction with GABA-induced inhibition were assessed in the rat medial basal hypothalamus both in situ and in explant culture. In situ, valproate enhanced the spontaneous rate in 14 of 20 neurons sampled, 6 neurons were unaffected. In vitro, valproate had an inconsistent effect on firing rate; the spontaneous rate was decreased in 6 cells, elevated in 1, while 17 either were unchanged or demonstrated no consistent pattern of response. Both in vivo and in vitro, valproate produced a variable effect on GABA induced inhibition. In vivo, the modal response of valproate on GABA inhibition was antagonism whereas the response in vitro was less consistent, favoring no change in GABA inhibition. The results of this study suggest that valproate exerts an inconsistent action on hypothalamic neurons. These findings are in contrast to those from the cerebral cortex, suggesting that the action of valproate in the brain may be regionally specific." @default.
- W1979409715 created "2016-06-24" @default.
- W1979409715 creator A5004338485 @default.
- W1979409715 creator A5027318950 @default.
- W1979409715 date "1981-08-01" @default.
- W1979409715 modified "2023-09-24" @default.
- W1979409715 title "Effect of sodium valporate on hypothalamic neurons in vivo and in vitro" @default.
- W1979409715 cites W1971489137 @default.
- W1979409715 cites W1984114233 @default.
- W1979409715 cites W1988765602 @default.
- W1979409715 cites W1990310107 @default.
- W1979409715 cites W2004476309 @default.
- W1979409715 cites W2016648385 @default.
- W1979409715 cites W2029618834 @default.
- W1979409715 cites W2029750871 @default.
- W1979409715 cites W2030473049 @default.
- W1979409715 cites W2030710786 @default.
- W1979409715 cites W2080409381 @default.
- W1979409715 cites W2082300590 @default.
- W1979409715 cites W2083313877 @default.
- W1979409715 cites W2083744170 @default.
- W1979409715 cites W2171369820 @default.
- W1979409715 doi "https://doi.org/10.1016/0006-8993(81)90288-2" @default.
- W1979409715 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6790130" @default.
- W1979409715 hasPublicationYear "1981" @default.
- W1979409715 type Work @default.
- W1979409715 sameAs 1979409715 @default.
- W1979409715 citedByCount "27" @default.
- W1979409715 countsByYear W19794097152013 @default.
- W1979409715 countsByYear W19794097152015 @default.
- W1979409715 countsByYear W19794097152016 @default.
- W1979409715 countsByYear W19794097152020 @default.
- W1979409715 crossrefType "journal-article" @default.
- W1979409715 hasAuthorship W1979409715A5004338485 @default.
- W1979409715 hasAuthorship W1979409715A5027318950 @default.
- W1979409715 hasConcept C126322002 @default.
- W1979409715 hasConcept C134018914 @default.
- W1979409715 hasConcept C150903083 @default.
- W1979409715 hasConcept C169760540 @default.
- W1979409715 hasConcept C17077164 @default.
- W1979409715 hasConcept C185592680 @default.
- W1979409715 hasConcept C202751555 @default.
- W1979409715 hasConcept C207001950 @default.
- W1979409715 hasConcept C2777003273 @default.
- W1979409715 hasConcept C2781041448 @default.
- W1979409715 hasConcept C55493867 @default.
- W1979409715 hasConcept C71924100 @default.
- W1979409715 hasConcept C86803240 @default.
- W1979409715 hasConceptScore W1979409715C126322002 @default.
- W1979409715 hasConceptScore W1979409715C134018914 @default.
- W1979409715 hasConceptScore W1979409715C150903083 @default.
- W1979409715 hasConceptScore W1979409715C169760540 @default.
- W1979409715 hasConceptScore W1979409715C17077164 @default.
- W1979409715 hasConceptScore W1979409715C185592680 @default.
- W1979409715 hasConceptScore W1979409715C202751555 @default.
- W1979409715 hasConceptScore W1979409715C207001950 @default.
- W1979409715 hasConceptScore W1979409715C2777003273 @default.
- W1979409715 hasConceptScore W1979409715C2781041448 @default.
- W1979409715 hasConceptScore W1979409715C55493867 @default.
- W1979409715 hasConceptScore W1979409715C71924100 @default.
- W1979409715 hasConceptScore W1979409715C86803240 @default.
- W1979409715 hasIssue "1" @default.
- W1979409715 hasLocation W19794097151 @default.
- W1979409715 hasLocation W19794097152 @default.
- W1979409715 hasOpenAccess W1979409715 @default.
- W1979409715 hasPrimaryLocation W19794097151 @default.
- W1979409715 hasRelatedWork W2000903685 @default.
- W1979409715 hasRelatedWork W2036117787 @default.
- W1979409715 hasRelatedWork W2051488242 @default.
- W1979409715 hasRelatedWork W2056116732 @default.
- W1979409715 hasRelatedWork W2065984027 @default.
- W1979409715 hasRelatedWork W2066173879 @default.
- W1979409715 hasRelatedWork W2070793461 @default.
- W1979409715 hasRelatedWork W2084435836 @default.
- W1979409715 hasRelatedWork W2773858965 @default.
- W1979409715 hasRelatedWork W2023428246 @default.
- W1979409715 hasVolume "219" @default.
- W1979409715 isParatext "false" @default.
- W1979409715 isRetracted "false" @default.
- W1979409715 magId "1979409715" @default.
- W1979409715 workType "article" @default.