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- W1979411772 abstract "Warm microemulsions based on lipids characterized by a melting point over 50 degrees C have been successfully used as starting matrix in a quenching process to obtain solid lipid nanoparticles (SLN). In this work, we have investigated the effect of 1-butanol (B) on the phase behavior of the lecithin (LCT)/water (W)/tripalmitin (TP) system at 70 degrees C. The study has been carried out at LCT/B=1 (weight ratio). Emulsion and liquid crystalline phase regions have been observed in the ternary phase diagram, while the presence of 1-butanol in the LCT/W/B/TP system allows the formation of a wide area of liquid isotropic phase from the whole (LCT+B)/TP binary axis up to 37 wt% of water. The microstructure of this isotropic phase has been investigated by means of 1H NMR PGSE technique. The self-diffusion coefficients of the different components along oil and water dilution lines indicate a microstructural organization characterized by a highly connected water in oil domains." @default.
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- W1979411772 date "2005-06-01" @default.
- W1979411772 modified "2023-10-17" @default.
- W1979411772 title "Effect of 1-butanol on the microstructure of lecithin/water/tripalmitin system" @default.
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- W1979411772 doi "https://doi.org/10.1016/j.chemphyslip.2005.02.010" @default.
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