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- W1979423195 abstract "Nonequilibrium molecular dynamics simulations were used to calculate the elastic properties of a spectrin repeat unit. A contiguous alpha-helical linker was constructed by employing periodic boundary conditions, allowing a novel scheme for evaluating the thermodynamic force as a function of extension. By measuring the force-extension response under small extensions, spectrin was observed to behave primarily as an elastic material with a spring constant of 1700 +/- 100 pN/nm. The implications of this spring constant, in terms of the properties of the spectrin tetramer, are also discussed." @default.
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- W1979423195 date "2006-01-01" @default.
- W1979423195 modified "2023-09-28" @default.
- W1979423195 title "Extending a Spectrin Repeat Unit. I: Linear Force-Extension Response" @default.
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- W1979423195 doi "https://doi.org/10.1529/biophysj.105.066969" @default.
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