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- W1979449568 abstract "Objectives: To evaluate the rate of preterm delivery (PTD) following late amniocentesis (>24 weeks of gestation). Methods: A retrospective cohort of all women with singleton pregnancy who underwent late amniocentesis in one tertiary center between 2005–2009, due to various indications, excluding cases of suspected amnionitis or premature rupture of membranes. Results: The initial cohort included 182 women. Pregnancy outcome was validated in 158 women who underwent amniocentesis at 24–36 weeks of gestation (mean, 31.4 ± 1.9). 13 women were excluded due to premature labor induction or cesarean section for suspected IUGR. Indications for late amniocentesis included abnormal ultrasonographic findings (n = 98), suspected intrauterine CMV or toxoplasmosis infection (n = 19), maternal age (n = 13), abnormal first or second trimester biochemical markers (n = 8) and others (n = 7). The rate of spontaneous PTD (<37 weeks) was 8.9% (13/145), mean gestational age at delivery 34.7 ± 1.3 (32–36 weeks). In only 5 (3.4%) delivery occurred ≤34 weeks of gestation. In one case (0.68%) of amniocentesis performed at 32 weeks of gestation, delivery occurred within 48 hours. In 4 cases (2.75%) delivery occurred within 10 day. The rate of PTD and mean gestational age at delivery stratified by grouped gestational age at amniocentesis is presented at Table 1. If cases of amniocentesis performed for ultrasonographic findings to rule out chromosomal abnormalities (n = 117/182), abnormal karyotype was found in 3 cases (2.56%). Conclusions: The risk of significant prematurity following late amniocentesis is low." @default.
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- W1979449568 date "2010-10-01" @default.
- W1979449568 modified "2023-10-03" @default.
- W1979449568 title "P09.19: Fetal loss and complications after genetic amniocentesis" @default.
- W1979449568 doi "https://doi.org/10.1002/uog.8437" @default.
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