FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1979511881> ?p ?o ?g. }

• W1979511881 endingPage "11" @default.
• W1979511881 startingPage "5" @default.
• W1979511881 abstract "Sinomenine is an alkaloid originally isolated from the root of the plant Sinomenium acutum. It is used in traditional medicine in China to treat rheumatic arthritis. In the present study, we evaluated the potential antinociceptive effects of sinomenine in rodents with nociceptive, inflammatory and neuropathic pain. In normal rats and mice, systemic sinomenine produced moderate antinociceptive effect in the hot plate and tail flick tests. Sinomenine also exerted analgesic effects on mechanical and heat hypersensitivity in mice after carrageenan induced inflammation. Finally, sinomenine effectively alleviated mechanical and cold allodynia in rats and mice after injury to peripheral nerve or spinal cord. The analgesic effect of sinomenine is not associated with side effects and is not reversed by the opioid receptor antagonist naloxone. Our results showed that sinomenine has a wide spectrum analgesic effect in rodent models of nociceptive, inflammatory and neuropathic pain." @default.
• W1979511881 created "2016-06-24" @default.
• W1979511881 creator A5028058399 @default.
• W1979511881 creator A5050969311 @default.
• W1979511881 creator A5055926195 @default.
• W1979511881 creator A5056388603 @default.
• W1979511881 creator A5057355735 @default.
• W1979511881 date "2013-12-01" @default.
• W1979511881 modified "2023-10-03" @default.
• W1979511881 title "Analgesic effect of sinomenine in rodents after inflammation and nerve injury" @default.
• W1979511881 cites W1556346068 @default.
• W1979511881 cites W1979288311 @default.
• W1979511881 cites W1986237413 @default.
• W1979511881 cites W1993397513 @default.
• W1979511881 cites W2017640872 @default.
• W1979511881 cites W2029396512 @default.
• W1979511881 cites W2035722419 @default.
• W1979511881 cites W2043299767 @default.
• W1979511881 cites W2043343458 @default.
• W1979511881 cites W2046399807 @default.
• W1979511881 cites W2049445327 @default.
• W1979511881 cites W2050504180 @default.
• W1979511881 cites W2051796859 @default.
• W1979511881 cites W2053773901 @default.
• W1979511881 cites W2056696036 @default.
• W1979511881 cites W2057882856 @default.
• W1979511881 cites W2071862338 @default.
• W1979511881 cites W2072382110 @default.
• W1979511881 cites W2075265720 @default.
• W1979511881 cites W2078725840 @default.
• W1979511881 cites W2079692119 @default.
• W1979511881 cites W2080281956 @default.
• W1979511881 cites W2081997720 @default.
• W1979511881 cites W2092918915 @default.
• W1979511881 cites W2103368328 @default.
• W1979511881 cites W2135247591 @default.
• W1979511881 cites W2136614669 @default.
• W1979511881 cites W2139635582 @default.
• W1979511881 cites W2140193821 @default.
• W1979511881 cites W2164513741 @default.
• W1979511881 cites W2167613032 @default.
• W1979511881 cites W4211164730 @default.
• W1979511881 cites W1499252636 @default.
• W1979511881 doi "https://doi.org/10.1016/j.ejphar.2013.09.062" @default.
• W1979511881 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24120369" @default.
• W1979511881 hasPublicationYear "2013" @default.
• W1979511881 type Work @default.
• W1979511881 sameAs 1979511881 @default.
• W1979511881 citedByCount "70" @default.
• W1979511881 countsByYear W19795118812014 @default.
• W1979511881 countsByYear W19795118812015 @default.
• W1979511881 countsByYear W19795118812016 @default.
• W1979511881 countsByYear W19795118812017 @default.
• W1979511881 countsByYear W19795118812018 @default.
• W1979511881 countsByYear W19795118812019 @default.
• W1979511881 countsByYear W19795118812020 @default.
• W1979511881 countsByYear W19795118812021 @default.
• W1979511881 countsByYear W19795118812022 @default.
• W1979511881 countsByYear W19795118812023 @default.
• W1979511881 crossrefType "journal-article" @default.
• W1979511881 hasAuthorship W1979511881A5028058399 @default.
• W1979511881 hasAuthorship W1979511881A5050969311 @default.
• W1979511881 hasAuthorship W1979511881A5055926195 @default.
• W1979511881 hasAuthorship W1979511881A5056388603 @default.
• W1979511881 hasAuthorship W1979511881A5057355735 @default.
• W1979511881 hasConcept C126322002 @default.
• W1979511881 hasConcept C15490471 @default.
• W1979511881 hasConcept C170493617 @default.
• W1979511881 hasConcept C2776885963 @default.
• W1979511881 hasConcept C2777107010 @default.
• W1979511881 hasConcept C2777662524 @default.
• W1979511881 hasConcept C2777883359 @default.
• W1979511881 hasConcept C2778750930 @default.
• W1979511881 hasConcept C2779245659 @default.
• W1979511881 hasConcept C2780820201 @default.
• W1979511881 hasConcept C42219234 @default.
• W1979511881 hasConcept C71924100 @default.
• W1979511881 hasConcept C98274493 @default.
• W1979511881 hasConceptScore W1979511881C126322002 @default.
• W1979511881 hasConceptScore W1979511881C15490471 @default.
• W1979511881 hasConceptScore W1979511881C170493617 @default.
• W1979511881 hasConceptScore W1979511881C2776885963 @default.
• W1979511881 hasConceptScore W1979511881C2777107010 @default.
• W1979511881 hasConceptScore W1979511881C2777662524 @default.
• W1979511881 hasConceptScore W1979511881C2777883359 @default.
• W1979511881 hasConceptScore W1979511881C2778750930 @default.
• W1979511881 hasConceptScore W1979511881C2779245659 @default.
• W1979511881 hasConceptScore W1979511881C2780820201 @default.
• W1979511881 hasConceptScore W1979511881C42219234 @default.
• W1979511881 hasConceptScore W1979511881C71924100 @default.
• W1979511881 hasConceptScore W1979511881C98274493 @default.
• W1979511881 hasIssue "1-3" @default.
• W1979511881 hasLocation W19795118811 @default.
• W1979511881 hasLocation W19795118812 @default.
• W1979511881 hasOpenAccess W1979511881 @default.
• W1979511881 hasPrimaryLocation W19795118811 @default.
• W1979511881 hasRelatedWork W1973635002 @default.
• W1979511881 hasRelatedWork W1979511881 @default.

• next