Matches in SemOpenAlex for { <https://semopenalex.org/work/W1979523129> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W1979523129 endingPage "130" @default.
- W1979523129 startingPage "123" @default.
- W1979523129 abstract "To evaluate the effects of Phyllanthus extracts on mechanical hyperalgesia induced by repeated intramuscular injections of acidic saline. The standardized aqueous extract of Phyllanthus amarus whole plant (PAAE), Standardized methanolic extract of P. amarus leaf (PAEE), the standardized hydro-methanolic extract of P. amarus leaf (PAHEE) and standardized hydroethanolic extract of P. fraternus whole plant (PFHEE) were tested in the fibromyalgic model of acid-induced chronic pain in the rats. Mechanical hyperalgesia was assessed by measuring the withdrawal thresholds to mechanical stimuli both to the ipsilateral as well as to the contralateral paws. On 22nd day, the animals were sacrificed and the gastrocnemius muscle at the site of injection was dissected for histopathological studies. PAAE, PAEE, PAHEE and PFHEE increased the mechanical withdrawal threshold (mechanical hyperalgesia) back towards the baseline responses. The percentage of maximum possible effectiveness and percentage inhibition of hyperalgesia also revealed the efficacy of Phyllanthus extracts. The multidose strategy did not cause tolerance. The results of the present study suggest that in the present model, muscle-mediated pain can be alleviated by standardized extracts of Phyllanthus species and suggest that these can be useful in treatment of chronic musculoskeletal pain syndromes such as fibromyalgia." @default.
- W1979523129 created "2016-06-24" @default.
- W1979523129 creator A5039472131 @default.
- W1979523129 creator A5070419831 @default.
- W1979523129 date "2014-04-01" @default.
- W1979523129 modified "2023-10-18" @default.
- W1979523129 title "Antifibromyalgic activity of standardized extracts of Phyllanthus amarus and Phyllanthus fraternus in acidic saline induced chronic muscle pain" @default.
- W1979523129 cites W124071055 @default.
- W1979523129 cites W1965406171 @default.
- W1979523129 cites W1965565026 @default.
- W1979523129 cites W1973667353 @default.
- W1979523129 cites W1983338861 @default.
- W1979523129 cites W1986510237 @default.
- W1979523129 cites W2009399717 @default.
- W1979523129 cites W2011717482 @default.
- W1979523129 cites W2014965141 @default.
- W1979523129 cites W2027901315 @default.
- W1979523129 cites W2028812611 @default.
- W1979523129 cites W2029317047 @default.
- W1979523129 cites W2030617634 @default.
- W1979523129 cites W2042834458 @default.
- W1979523129 cites W2052596945 @default.
- W1979523129 cites W2078775197 @default.
- W1979523129 cites W2083266787 @default.
- W1979523129 cites W2083910964 @default.
- W1979523129 cites W2084888887 @default.
- W1979523129 cites W2108006450 @default.
- W1979523129 cites W2122560536 @default.
- W1979523129 cites W2128692107 @default.
- W1979523129 cites W2145694499 @default.
- W1979523129 cites W2147995249 @default.
- W1979523129 cites W2155715632 @default.
- W1979523129 cites W2167141095 @default.
- W1979523129 cites W2244305179 @default.
- W1979523129 cites W2395101681 @default.
- W1979523129 cites W2411936588 @default.
- W1979523129 doi "https://doi.org/10.1016/j.biomag.2014.01.005" @default.
- W1979523129 hasPublicationYear "2014" @default.
- W1979523129 type Work @default.
- W1979523129 sameAs 1979523129 @default.
- W1979523129 citedByCount "11" @default.
- W1979523129 countsByYear W19795231292015 @default.
- W1979523129 countsByYear W19795231292016 @default.
- W1979523129 countsByYear W19795231292018 @default.
- W1979523129 countsByYear W19795231292020 @default.
- W1979523129 countsByYear W19795231292021 @default.
- W1979523129 countsByYear W19795231292022 @default.
- W1979523129 countsByYear W19795231292023 @default.
- W1979523129 crossrefType "journal-article" @default.
- W1979523129 hasAuthorship W1979523129A5039472131 @default.
- W1979523129 hasAuthorship W1979523129A5070419831 @default.
- W1979523129 hasConcept C126322002 @default.
- W1979523129 hasConcept C15490471 @default.
- W1979523129 hasConcept C170493617 @default.
- W1979523129 hasConcept C2776718122 @default.
- W1979523129 hasConcept C2777397205 @default.
- W1979523129 hasConcept C2779245659 @default.
- W1979523129 hasConcept C42219234 @default.
- W1979523129 hasConcept C556039675 @default.
- W1979523129 hasConcept C71924100 @default.
- W1979523129 hasConcept C98274493 @default.
- W1979523129 hasConceptScore W1979523129C126322002 @default.
- W1979523129 hasConceptScore W1979523129C15490471 @default.
- W1979523129 hasConceptScore W1979523129C170493617 @default.
- W1979523129 hasConceptScore W1979523129C2776718122 @default.
- W1979523129 hasConceptScore W1979523129C2777397205 @default.
- W1979523129 hasConceptScore W1979523129C2779245659 @default.
- W1979523129 hasConceptScore W1979523129C42219234 @default.
- W1979523129 hasConceptScore W1979523129C556039675 @default.
- W1979523129 hasConceptScore W1979523129C71924100 @default.
- W1979523129 hasConceptScore W1979523129C98274493 @default.
- W1979523129 hasIssue "2" @default.
- W1979523129 hasLocation W19795231291 @default.
- W1979523129 hasOpenAccess W1979523129 @default.
- W1979523129 hasPrimaryLocation W19795231291 @default.
- W1979523129 hasRelatedWork W1500770553 @default.
- W1979523129 hasRelatedWork W1976105490 @default.
- W1979523129 hasRelatedWork W2014007136 @default.
- W1979523129 hasRelatedWork W2049912867 @default.
- W1979523129 hasRelatedWork W2610309228 @default.
- W1979523129 hasRelatedWork W2992764783 @default.
- W1979523129 hasRelatedWork W3138919747 @default.
- W1979523129 hasRelatedWork W4285320868 @default.
- W1979523129 hasRelatedWork W2732998902 @default.
- W1979523129 hasRelatedWork W593781739 @default.
- W1979523129 hasVolume "4" @default.
- W1979523129 isParatext "false" @default.
- W1979523129 isRetracted "false" @default.
- W1979523129 magId "1979523129" @default.
- W1979523129 workType "article" @default.