Matches in SemOpenAlex for { <https://semopenalex.org/work/W1979530545> ?p ?o ?g. }
- W1979530545 endingPage "17" @default.
- W1979530545 startingPage "7" @default.
- W1979530545 abstract "In apical membrane vesicles from beef tracheal epithelia expressing up to 30% of the proteins as functional cystic fibrosis transmembrane conductance regulator (CFTR)-- i.e. a voltage-independent and PKA-sensitive 36Cl- flux--an ATPase activity, different from P, F0F1 and V types, was reproducibly detected. Its specific activity averaged 20 micromol Pi h(-1) mg(-1) with an apparent affinity for ATP of 530 +/- 30 microM. Its possible involvement in CFTR functions was supported by (1) the linear relationship between the ATPase activity and the magnitude of 36Cl- fluxes (turnover rate: 3 ATP hydrolyzed per CFTR per second), (2) the same rank of potency of ATP, ITP, GTP, UTP and CTP to be hydrolyzed and to open CFTR chloride channels, (3) the similar and parallel inhibition of the ATPase and CFTR Cl- fluxes by NS004 (IC50: 60 microM) and (4) the potency of anti-R domain antibodies to increase by 18% the ATPase activity." @default.
- W1979530545 created "2016-06-24" @default.
- W1979530545 creator A5035678172 @default.
- W1979530545 creator A5057761078 @default.
- W1979530545 date "2000-07-01" @default.
- W1979530545 modified "2023-10-01" @default.
- W1979530545 title "Biochemical evidence for ATPase activity in CFTR-enriched apical membrane vesicles from tracheal epithelium" @default.
- W1979530545 cites W1516227220 @default.
- W1979530545 cites W1523858318 @default.
- W1979530545 cites W1554937054 @default.
- W1979530545 cites W1590184168 @default.
- W1979530545 cites W1637725071 @default.
- W1979530545 cites W1775749144 @default.
- W1979530545 cites W1857201556 @default.
- W1979530545 cites W1965343672 @default.
- W1979530545 cites W1971465332 @default.
- W1979530545 cites W1982011740 @default.
- W1979530545 cites W1982625622 @default.
- W1979530545 cites W1990687915 @default.
- W1979530545 cites W1996751588 @default.
- W1979530545 cites W2010226740 @default.
- W1979530545 cites W2010691166 @default.
- W1979530545 cites W2013541526 @default.
- W1979530545 cites W2039599894 @default.
- W1979530545 cites W2043502964 @default.
- W1979530545 cites W2047930213 @default.
- W1979530545 cites W2055241554 @default.
- W1979530545 cites W2059043844 @default.
- W1979530545 cites W2060670045 @default.
- W1979530545 cites W2075257287 @default.
- W1979530545 cites W2077549324 @default.
- W1979530545 cites W2078282757 @default.
- W1979530545 cites W2082244393 @default.
- W1979530545 cites W2100837269 @default.
- W1979530545 cites W2101108802 @default.
- W1979530545 cites W2126150822 @default.
- W1979530545 cites W2156523433 @default.
- W1979530545 cites W2161220285 @default.
- W1979530545 cites W2426211207 @default.
- W1979530545 cites W89071597 @default.
- W1979530545 doi "https://doi.org/10.1016/s0005-2736(00)00187-5" @default.
- W1979530545 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10930504" @default.
- W1979530545 hasPublicationYear "2000" @default.
- W1979530545 type Work @default.
- W1979530545 sameAs 1979530545 @default.
- W1979530545 citedByCount "0" @default.
- W1979530545 crossrefType "journal-article" @default.
- W1979530545 hasAuthorship W1979530545A5035678172 @default.
- W1979530545 hasAuthorship W1979530545A5057761078 @default.
- W1979530545 hasBestOaLocation W19795305451 @default.
- W1979530545 hasConcept C104317684 @default.
- W1979530545 hasConcept C118716 @default.
- W1979530545 hasConcept C130316041 @default.
- W1979530545 hasConcept C141315368 @default.
- W1979530545 hasConcept C145822097 @default.
- W1979530545 hasConcept C170493617 @default.
- W1979530545 hasConcept C181199279 @default.
- W1979530545 hasConcept C185592680 @default.
- W1979530545 hasConcept C202751555 @default.
- W1979530545 hasConcept C23265538 @default.
- W1979530545 hasConcept C24530287 @default.
- W1979530545 hasConcept C2778428886 @default.
- W1979530545 hasConcept C3018436504 @default.
- W1979530545 hasConcept C41625074 @default.
- W1979530545 hasConcept C55493867 @default.
- W1979530545 hasConcept C57992300 @default.
- W1979530545 hasConceptScore W1979530545C104317684 @default.
- W1979530545 hasConceptScore W1979530545C118716 @default.
- W1979530545 hasConceptScore W1979530545C130316041 @default.
- W1979530545 hasConceptScore W1979530545C141315368 @default.
- W1979530545 hasConceptScore W1979530545C145822097 @default.
- W1979530545 hasConceptScore W1979530545C170493617 @default.
- W1979530545 hasConceptScore W1979530545C181199279 @default.
- W1979530545 hasConceptScore W1979530545C185592680 @default.
- W1979530545 hasConceptScore W1979530545C202751555 @default.
- W1979530545 hasConceptScore W1979530545C23265538 @default.
- W1979530545 hasConceptScore W1979530545C24530287 @default.
- W1979530545 hasConceptScore W1979530545C2778428886 @default.
- W1979530545 hasConceptScore W1979530545C3018436504 @default.
- W1979530545 hasConceptScore W1979530545C41625074 @default.
- W1979530545 hasConceptScore W1979530545C55493867 @default.
- W1979530545 hasConceptScore W1979530545C57992300 @default.
- W1979530545 hasIssue "1" @default.
- W1979530545 hasLocation W19795305451 @default.
- W1979530545 hasLocation W19795305452 @default.
- W1979530545 hasOpenAccess W1979530545 @default.
- W1979530545 hasPrimaryLocation W19795305451 @default.
- W1979530545 hasRelatedWork W1632224638 @default.
- W1979530545 hasRelatedWork W1968164965 @default.
- W1979530545 hasRelatedWork W1979530545 @default.
- W1979530545 hasRelatedWork W1998199476 @default.
- W1979530545 hasRelatedWork W2037241846 @default.
- W1979530545 hasRelatedWork W2063892985 @default.
- W1979530545 hasRelatedWork W2120379586 @default.
- W1979530545 hasRelatedWork W2124848891 @default.
- W1979530545 hasRelatedWork W2162916802 @default.
- W1979530545 hasRelatedWork W2931983458 @default.
- W1979530545 hasVolume "1467" @default.