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- W1979553887 abstract "Cholestyramine, an insoluble anion exchange resin which absorbs bile acids in theintestine, was given orally to two siblings with familial hypercholesterolemia. A 3 week course of 9 Gm. of the drug each day failed to alter the plasma cholesterol concentration. However, after a 3 week course of 15 Gm. daily of the drug, there was a lowering of plasma cholesterol levels by 12 to 44 per cent of control values. No toxic effects were noted. This drug appears to warrant further trial in individuals with familial hypercholesterolemia. Cholestyramine, an insoluble anion exchange resin which absorbs bile acids in theintestine, was given orally to two siblings with familial hypercholesterolemia. A 3 week course of 9 Gm. of the drug each day failed to alter the plasma cholesterol concentration. However, after a 3 week course of 15 Gm. daily of the drug, there was a lowering of plasma cholesterol levels by 12 to 44 per cent of control values. No toxic effects were noted. This drug appears to warrant further trial in individuals with familial hypercholesterolemia." @default.
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- W1979553887 date "1964-02-01" @default.
- W1979553887 modified "2023-09-26" @default.
- W1979553887 title "Use of an anion exchange resin in treatment of two siblings with familial hypercholesterolemia" @default.
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- W1979553887 doi "https://doi.org/10.1016/s0022-3476(64)80263-8" @default.
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