FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1979576470> ?p ?o ?g. }

• W1979576470 endingPage "412" @default.
• W1979576470 startingPage "407" @default.
• W1979576470 abstract "Some novel tachykinin peptides exhibiting homology with known members of the tachykinin family have been recently reported; however, little is known about the function of these peptides. Repeated intrathecal administration of substance P (SP) causes desensitization by binding SP to neurokinin 1 (NK1) receptor. Thus, to clarify the characteristics of the receptors involved in these novel peptides, we investigated whether desensitization is induced by intrathecal administration of these peptides in rats since desensitization is induced by binding these peptides to the receptor. Intrathecal administration of 10−3 M hemokinin-1 (HK-1) and 10−3 M decapeptide common in the carboxyl-terminal region of endokinin A and endokinin B (EKA/B) as well as SP evoked scratching behavior. When each peptide was administered twice with an interval of 15 min, remarkable desensitization of scratching behavior was produced. Furthermore, the first administration of EKA/B or SP produced clear cross-desensitization to SP, EKA/B and HK-1, whereas the first administration of HK-1 demonstrated weak cross-desensitization to EKA/B and SP. These results suggest that EKA/B and SP may bind to both the NK1 receptor and HK-1-preferred receptor, and HK-1 may preferentially bind to its preferred receptor." @default.
• W1979576470 created "2016-06-24" @default.
• W1979576470 creator A5014612415 @default.
• W1979576470 creator A5030566351 @default.
• W1979576470 creator A5040550965 @default.
• W1979576470 creator A5044203559 @default.
• W1979576470 date "1981-04-01" @default.
• W1979576470 modified "2023-09-25" @default.
• W1979576470 title "Behavioral evidence that substance P may be a spinal cord sensory neurotransmitter" @default.
• W1979576470 cites W1836161604 @default.
• W1979576470 cites W1968115871 @default.
• W1979576470 cites W1972416469 @default.
• W1979576470 cites W1979350446 @default.
• W1979576470 cites W1986589058 @default.
• W1979576470 cites W1986671514 @default.
• W1979576470 cites W1988967982 @default.
• W1979576470 cites W2003581757 @default.
• W1979576470 cites W2004624137 @default.
• W1979576470 cites W2005136572 @default.
• W1979576470 cites W2012923655 @default.
• W1979576470 cites W2018080111 @default.
• W1979576470 cites W2021400191 @default.
• W1979576470 cites W2037175122 @default.
• W1979576470 cites W2045091557 @default.
• W1979576470 cites W2047168929 @default.
• W1979576470 cites W2053745334 @default.
• W1979576470 cites W2057615421 @default.
• W1979576470 cites W2069306418 @default.
• W1979576470 cites W2070868453 @default.
• W1979576470 cites W2091419509 @default.
• W1979576470 cites W2092003861 @default.
• W1979576470 cites W2143141394 @default.
• W1979576470 cites W4236750954 @default.
• W1979576470 cites W4376595418 @default.
• W1979576470 cites W990169342 @default.
• W1979576470 doi "https://doi.org/10.1016/0006-8993(81)90918-5" @default.
• W1979576470 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6164445" @default.
• W1979576470 hasPublicationYear "1981" @default.
• W1979576470 type Work @default.
• W1979576470 sameAs 1979576470 @default.
• W1979576470 citedByCount "150" @default.
• W1979576470 countsByYear W19795764702012 @default.
• W1979576470 countsByYear W19795764702016 @default.
• W1979576470 countsByYear W19795764702017 @default.
• W1979576470 crossrefType "journal-article" @default.
• W1979576470 hasAuthorship W1979576470A5014612415 @default.
• W1979576470 hasAuthorship W1979576470A5030566351 @default.
• W1979576470 hasAuthorship W1979576470A5040550965 @default.
• W1979576470 hasAuthorship W1979576470A5044203559 @default.
• W1979576470 hasConcept C118303440 @default.
• W1979576470 hasConcept C126322002 @default.
• W1979576470 hasConcept C134018914 @default.
• W1979576470 hasConcept C169760540 @default.
• W1979576470 hasConcept C170493617 @default.
• W1979576470 hasConcept C185592680 @default.
• W1979576470 hasConcept C2776219046 @default.
• W1979576470 hasConcept C2776533618 @default.
• W1979576470 hasConcept C2779779143 @default.
• W1979576470 hasConcept C2780775167 @default.
• W1979576470 hasConcept C2781359426 @default.
• W1979576470 hasConcept C55493867 @default.
• W1979576470 hasConcept C55938493 @default.
• W1979576470 hasConcept C71924100 @default.
• W1979576470 hasConcept C86803240 @default.
• W1979576470 hasConcept C98274493 @default.
• W1979576470 hasConceptScore W1979576470C118303440 @default.
• W1979576470 hasConceptScore W1979576470C126322002 @default.
• W1979576470 hasConceptScore W1979576470C134018914 @default.
• W1979576470 hasConceptScore W1979576470C169760540 @default.
• W1979576470 hasConceptScore W1979576470C170493617 @default.
• W1979576470 hasConceptScore W1979576470C185592680 @default.
• W1979576470 hasConceptScore W1979576470C2776219046 @default.
• W1979576470 hasConceptScore W1979576470C2776533618 @default.
• W1979576470 hasConceptScore W1979576470C2779779143 @default.
• W1979576470 hasConceptScore W1979576470C2780775167 @default.
• W1979576470 hasConceptScore W1979576470C2781359426 @default.
• W1979576470 hasConceptScore W1979576470C55493867 @default.
• W1979576470 hasConceptScore W1979576470C55938493 @default.
• W1979576470 hasConceptScore W1979576470C71924100 @default.
• W1979576470 hasConceptScore W1979576470C86803240 @default.
• W1979576470 hasConceptScore W1979576470C98274493 @default.
• W1979576470 hasIssue "1-2" @default.
• W1979576470 hasLocation W19795764701 @default.
• W1979576470 hasLocation W19795764702 @default.
• W1979576470 hasOpenAccess W1979576470 @default.
• W1979576470 hasPrimaryLocation W19795764701 @default.
• W1979576470 hasRelatedWork W1243476613 @default.
• W1979576470 hasRelatedWork W1984741208 @default.
• W1979576470 hasRelatedWork W2009518509 @default.
• W1979576470 hasRelatedWork W2040489082 @default.
• W1979576470 hasRelatedWork W2047292942 @default.
• W1979576470 hasRelatedWork W2072311509 @default.
• W1979576470 hasRelatedWork W2075095107 @default.
• W1979576470 hasRelatedWork W2082847226 @default.
• W1979576470 hasRelatedWork W2150393025 @default.
• W1979576470 hasRelatedWork W3153217867 @default.
• W1979576470 hasVolume "210" @default.
• W1979576470 isParatext "false" @default.

• next