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- W1979610504 abstract "The effects of selective D1 and D2 antagonists, R-(+)-8-chloro-2,3,4,5,-tetrahydro-3-methyl-5-phenyl-1H-3-benzazepine-7-ol (SCH-23390) and sulpiride, on the transient increase of dopamine (DA) release induced by DA agonists, apomorphine (APO) and 2,3,4,5-tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine (SKF-38393) were examined in the caudate-putamen of freely moving rat by means of microdialysis during local coinfusion of a DA antagonist and agonist. Infusion of 10−5 M and/or 10−6 M concentrations of SCH-23390 suppressed a brief increase in DA release induced by both 10−4 M of APO and 10−5 M of SKF-38393. On the other hand, 10−5 M and/or 10−6 M of sulpiride exerted little or no effect. A possible explanation for this phenomenon was discussed." @default.
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- W1979610504 date "1991-11-01" @default.
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- W1979610504 title "Effects of D1 and D2 antagonists on the transient increase of dopamine release by dopamine agonists by means of brain dialysis" @default.
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- W1979610504 doi "https://doi.org/10.1016/0304-3940(91)90061-w" @default.
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