FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1979629145> ?p ?o ?g. }

• W1979629145 endingPage "231" @default.
• W1979629145 startingPage "225" @default.
• W1979629145 abstract "Abstract A systematic review of the literature was conducted to assess the outcomes of preventive interventions (prophylactic surgery, intensive cancer screening, and chemoprevention) in women who carry mutations in BRCA 1/2 genes, in terms of reducing breast and gynaecological cancer incidence and/or mortality. A search for relevant articles published between 1996 and 2005 (inclusive) was run on Medline, Embase and other databases. From the 749 journal articles retrieved from this search strategy, 18 studies were eligible for this review (2 systematic reviews, 10 cohort studies and 6 case‐control studies). The critical appraisal of the studies was performed by two independent reviewers with a list of ad hoc selected criteria. The synthesis of results was qualitative. Mastectomy and prophylactic gynaecological surgery (oophorectomy or salpingo‐oophorectomy) reduced breast and gynaecological cancer incidence in carriers of BRCA mutations, by comparison to surveillance. However, all the studies presented flaws in internal and external validity, none of these preventive interventions is risk‐free, and protection against breast and gynaecological cancer, as well as other cancers linked to BRCA mutations, is incomplete. No studies comparing surveillance programmes of varying intensity were found. Exposure to drugs (tamoxifen, and oral contraceptives) in women carrying BRCA mutations was assessed through a limited number of papers. All of these were case‐control studies with prevalent cases and presented major methodological flaws. © 2007 Wiley‐Liss, Inc." @default.
• W1979629145 created "2016-06-24" @default.
• W1979629145 creator A5043381836 @default.
• W1979629145 creator A5060110873 @default.
• W1979629145 creator A5065801587 @default.
• W1979629145 date "2007-05-18" @default.
• W1979629145 modified "2023-10-10" @default.
• W1979629145 title "Effectiveness of preventive interventions inBRCA1/2 gene mutation carriers: A systematic review" @default.
• W1979629145 cites W1593442063 @default.
• W1979629145 cites W1981703325 @default.
• W1979629145 cites W1988498963 @default.
• W1979629145 cites W1999793317 @default.
• W1979629145 cites W2009074196 @default.
• W1979629145 cites W2026628573 @default.
• W1979629145 cites W2033556486 @default.
• W1979629145 cites W2038793520 @default.
• W1979629145 cites W2045733577 @default.
• W1979629145 cites W2045986910 @default.
• W1979629145 cites W2046809735 @default.
• W1979629145 cites W2048140101 @default.
• W1979629145 cites W2062367399 @default.
• W1979629145 cites W2064786408 @default.
• W1979629145 cites W2069573564 @default.
• W1979629145 cites W2078829659 @default.
• W1979629145 cites W2085491990 @default.
• W1979629145 cites W2087145961 @default.
• W1979629145 cites W2101699473 @default.
• W1979629145 cites W2109203298 @default.
• W1979629145 cites W2109887368 @default.
• W1979629145 cites W2112339576 @default.
• W1979629145 cites W2113098178 @default.
• W1979629145 cites W2121537891 @default.
• W1979629145 cites W2137167442 @default.
• W1979629145 cites W2147058464 @default.
• W1979629145 cites W2150111967 @default.
• W1979629145 cites W2155862031 @default.
• W1979629145 cites W2161764786 @default.
• W1979629145 cites W2162096542 @default.
• W1979629145 cites W2167561774 @default.
• W1979629145 cites W2312752082 @default.
• W1979629145 cites W2332419565 @default.
• W1979629145 cites W2338185498 @default.
• W1979629145 doi "https://doi.org/10.1002/ijc.22817" @default.
• W1979629145 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17471565" @default.
• W1979629145 hasPublicationYear "2007" @default.
• W1979629145 type Work @default.
• W1979629145 sameAs 1979629145 @default.
• W1979629145 citedByCount "61" @default.
• W1979629145 countsByYear W19796291452012 @default.
• W1979629145 countsByYear W19796291452013 @default.
• W1979629145 countsByYear W19796291452014 @default.
• W1979629145 countsByYear W19796291452016 @default.
• W1979629145 countsByYear W19796291452017 @default.
• W1979629145 countsByYear W19796291452018 @default.
• W1979629145 countsByYear W19796291452020 @default.
• W1979629145 countsByYear W19796291452021 @default.
• W1979629145 crossrefType "journal-article" @default.
• W1979629145 hasAuthorship W1979629145A5043381836 @default.
• W1979629145 hasAuthorship W1979629145A5060110873 @default.
• W1979629145 hasAuthorship W1979629145A5065801587 @default.
• W1979629145 hasConcept C118552586 @default.
• W1979629145 hasConcept C120665830 @default.
• W1979629145 hasConcept C121332964 @default.
• W1979629145 hasConcept C121608353 @default.
• W1979629145 hasConcept C126322002 @default.
• W1979629145 hasConcept C141071460 @default.
• W1979629145 hasConcept C142724271 @default.
• W1979629145 hasConcept C143998085 @default.
• W1979629145 hasConcept C152541439 @default.
• W1979629145 hasConcept C17744445 @default.
• W1979629145 hasConcept C189708586 @default.
• W1979629145 hasConcept C199539241 @default.
• W1979629145 hasConcept C201903717 @default.
• W1979629145 hasConcept C204787440 @default.
• W1979629145 hasConcept C27415008 @default.
• W1979629145 hasConcept C2777176818 @default.
• W1979629145 hasConcept C2777696064 @default.
• W1979629145 hasConcept C2777757722 @default.
• W1979629145 hasConcept C2779473830 @default.
• W1979629145 hasConcept C2779494336 @default.
• W1979629145 hasConcept C2780194787 @default.
• W1979629145 hasConcept C2910039337 @default.
• W1979629145 hasConcept C2910584544 @default.
• W1979629145 hasConcept C29456083 @default.
• W1979629145 hasConcept C530470458 @default.
• W1979629145 hasConcept C61511704 @default.
• W1979629145 hasConcept C71924100 @default.
• W1979629145 hasConceptScore W1979629145C118552586 @default.
• W1979629145 hasConceptScore W1979629145C120665830 @default.
• W1979629145 hasConceptScore W1979629145C121332964 @default.
• W1979629145 hasConceptScore W1979629145C121608353 @default.
• W1979629145 hasConceptScore W1979629145C126322002 @default.
• W1979629145 hasConceptScore W1979629145C141071460 @default.
• W1979629145 hasConceptScore W1979629145C142724271 @default.
• W1979629145 hasConceptScore W1979629145C143998085 @default.
• W1979629145 hasConceptScore W1979629145C152541439 @default.
• W1979629145 hasConceptScore W1979629145C17744445 @default.
• W1979629145 hasConceptScore W1979629145C189708586 @default.

• next