Matches in SemOpenAlex for { <https://semopenalex.org/work/W1979681591> ?p ?o ?g. }
- W1979681591 endingPage "2060" @default.
- W1979681591 startingPage "2050" @default.
- W1979681591 abstract "The development of many animal organs involves a mesenchymal to epithelial transition, in which cells develop and coordinate polarity through largely unknown mechanisms. The C. elegans pharynx, which is an epithelial tube in which cells polarize around a central lumen, provides a simple system with which to understand the coordination of epithelial polarity. We show that cell fate regulators cause pharyngeal precursor cells to group into a bilaterally symmetric, rectangular array of cells called the double plate. The double plate cells polarize with apical localization of the PAR-3 protein complex, then undergo apical constriction to form a cylindrical cyst. We show that laminin, but not other basement membrane components, orients the polarity of the double plate cells. Our results provide in vivo evidence that laminin has an early role in cell polarity that can be distinguished from its later role in basement membrane integrity." @default.
- W1979681591 created "2016-06-24" @default.
- W1979681591 creator A5017130142 @default.
- W1979681591 creator A5064567519 @default.
- W1979681591 creator A5090351843 @default.
- W1979681591 date "2012-06-01" @default.
- W1979681591 modified "2023-10-02" @default.
- W1979681591 title "Laminin is required to orient epithelial polarity in the<i>C. elegans</i>pharynx" @default.
- W1979681591 cites W1533175630 @default.
- W1979681591 cites W1862598120 @default.
- W1979681591 cites W1924615382 @default.
- W1979681591 cites W1932156429 @default.
- W1979681591 cites W1944127002 @default.
- W1979681591 cites W1963709177 @default.
- W1979681591 cites W1964521956 @default.
- W1979681591 cites W1970466976 @default.
- W1979681591 cites W1971572255 @default.
- W1979681591 cites W1984163925 @default.
- W1979681591 cites W1989952069 @default.
- W1979681591 cites W1998556703 @default.
- W1979681591 cites W2005213594 @default.
- W1979681591 cites W2011124655 @default.
- W1979681591 cites W2011974546 @default.
- W1979681591 cites W2027785244 @default.
- W1979681591 cites W2029333097 @default.
- W1979681591 cites W2029469952 @default.
- W1979681591 cites W2033498252 @default.
- W1979681591 cites W2038492783 @default.
- W1979681591 cites W2040811742 @default.
- W1979681591 cites W2045428493 @default.
- W1979681591 cites W2049886990 @default.
- W1979681591 cites W2052584069 @default.
- W1979681591 cites W2052728159 @default.
- W1979681591 cites W2061593354 @default.
- W1979681591 cites W2067267062 @default.
- W1979681591 cites W2082522809 @default.
- W1979681591 cites W2089030810 @default.
- W1979681591 cites W2089747862 @default.
- W1979681591 cites W2090150346 @default.
- W1979681591 cites W2091189056 @default.
- W1979681591 cites W2091733078 @default.
- W1979681591 cites W2095718486 @default.
- W1979681591 cites W2101048878 @default.
- W1979681591 cites W2109791816 @default.
- W1979681591 cites W2110188006 @default.
- W1979681591 cites W2110359316 @default.
- W1979681591 cites W2110779290 @default.
- W1979681591 cites W2112510720 @default.
- W1979681591 cites W2119327651 @default.
- W1979681591 cites W2119352312 @default.
- W1979681591 cites W2121961422 @default.
- W1979681591 cites W2122163057 @default.
- W1979681591 cites W2127367210 @default.
- W1979681591 cites W2129018625 @default.
- W1979681591 cites W2129900247 @default.
- W1979681591 cites W2130995821 @default.
- W1979681591 cites W2133408521 @default.
- W1979681591 cites W2134891268 @default.
- W1979681591 cites W2137020823 @default.
- W1979681591 cites W2137339420 @default.
- W1979681591 cites W2139168014 @default.
- W1979681591 cites W2144876726 @default.
- W1979681591 cites W2145084130 @default.
- W1979681591 cites W2145468604 @default.
- W1979681591 cites W2148004059 @default.
- W1979681591 cites W2150019612 @default.
- W1979681591 cites W2153539961 @default.
- W1979681591 cites W2166254523 @default.
- W1979681591 cites W2166609159 @default.
- W1979681591 cites W2169968306 @default.
- W1979681591 cites W2331870214 @default.
- W1979681591 cites W2389928248 @default.
- W1979681591 cites W2417162181 @default.
- W1979681591 doi "https://doi.org/10.1242/dev.078360" @default.
- W1979681591 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3347693" @default.
- W1979681591 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22535412" @default.
- W1979681591 hasPublicationYear "2012" @default.
- W1979681591 type Work @default.
- W1979681591 sameAs 1979681591 @default.
- W1979681591 citedByCount "54" @default.
- W1979681591 countsByYear W19796815912012 @default.
- W1979681591 countsByYear W19796815912013 @default.
- W1979681591 countsByYear W19796815912014 @default.
- W1979681591 countsByYear W19796815912015 @default.
- W1979681591 countsByYear W19796815912016 @default.
- W1979681591 countsByYear W19796815912017 @default.
- W1979681591 countsByYear W19796815912018 @default.
- W1979681591 countsByYear W19796815912019 @default.
- W1979681591 countsByYear W19796815912020 @default.
- W1979681591 countsByYear W19796815912021 @default.
- W1979681591 countsByYear W19796815912022 @default.
- W1979681591 countsByYear W19796815912023 @default.
- W1979681591 crossrefType "journal-article" @default.
- W1979681591 hasAuthorship W1979681591A5017130142 @default.
- W1979681591 hasAuthorship W1979681591A5064567519 @default.
- W1979681591 hasAuthorship W1979681591A5090351843 @default.
- W1979681591 hasBestOaLocation W19796815911 @default.
- W1979681591 hasConcept C105702510 @default.