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- W1979695897 abstract "Objective We sought to identify patient characteristics associated with cervical intraepithelial neoplasia (CIN) 3 in adolescents. Study Design A cross-sectional cohort study was done using a colposcopic database. Data collected included demographic and clinical information as well as cytologic and histologic results. Variables associated with CIN 3 in the univariable analysis (P ≤ .10) were included in a multivariable logistic regression model. Results Of 614 adolescents evaluated, 48 (8%; 95% confidence interval, 6–10%) had CIN 3. No cancers were detected. In the univariable analysis, parity, ≥4 lifetime male sexual partners, and a history of sexually transmitted infections were associated with an increased risk of CIN 3. In the final model, only ≥4 sexual partners (compared to <4; adjusted odds ratio, 3.66; 95% confidence interval, 1.26–10.61) was significantly associated with the finding of CIN 3. Conclusion CIN 3 was infrequently encountered in adolescents, and those with multiple sexual partners were at increased risk for CIN 3. We sought to identify patient characteristics associated with cervical intraepithelial neoplasia (CIN) 3 in adolescents. A cross-sectional cohort study was done using a colposcopic database. Data collected included demographic and clinical information as well as cytologic and histologic results. Variables associated with CIN 3 in the univariable analysis (P ≤ .10) were included in a multivariable logistic regression model. Of 614 adolescents evaluated, 48 (8%; 95% confidence interval, 6–10%) had CIN 3. No cancers were detected. In the univariable analysis, parity, ≥4 lifetime male sexual partners, and a history of sexually transmitted infections were associated with an increased risk of CIN 3. In the final model, only ≥4 sexual partners (compared to <4; adjusted odds ratio, 3.66; 95% confidence interval, 1.26–10.61) was significantly associated with the finding of CIN 3. CIN 3 was infrequently encountered in adolescents, and those with multiple sexual partners were at increased risk for CIN 3." @default.
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- W1979695897 date "2011-02-01" @default.
- W1979695897 modified "2023-10-16" @default.
- W1979695897 title "Prevalence and patient characteristics associated with CIN 3 in adolescents" @default.
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- W1979695897 doi "https://doi.org/10.1016/j.ajog.2010.09.008" @default.
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