Matches in SemOpenAlex for { <https://semopenalex.org/work/W1979704228> ?p ?o ?g. }
- W1979704228 endingPage "282" @default.
- W1979704228 startingPage "274" @default.
- W1979704228 abstract "To clarify the biological behavior of TADG-14/KLK8, we investigated TADG-14/KLK8 mRNA by semiquantitative RT-PCR and hK8 expression by immunohistochemistry using 37 normal endometria and 44 endometrial carcinoma tissues. TADG-14/KLK8 mRNA expression levels were significantly higher in proliferative compared to secretory phase endometria (p = 0.0143). Levels of TADG-14/KLK8 mRNA expression correlated with hK8 protein levels. hK8 was detected in 73.3% (11/15) of endometria with a significantly higher detection rate in the proliferative compared to secretory and atrophic phase endometria (p = 0.0002). High expression of hK8 was found in 61.4% of endometrial carcinomas compared to 35.1% of endometrial tissue samples (p = 0.0187). hK8 expression was significantly higher in stage I (p = 0.0433, 0.0038) and grade 1/2 (G1/2) of the tumors (p = 0.0195, 0.0044). We suggest that expression of TADG-14/KLK8may be regulated by sex steroid hormones in endometria. Our results indicate that elevated TADG-14/KLK8 expression is an early event in endometrial carcinogenesis, and may potentially serve as a useful early biomarker for the detection of endometrial carcinomas in menopausal women." @default.
- W1979704228 created "2016-06-24" @default.
- W1979704228 creator A5012949887 @default.
- W1979704228 creator A5024093607 @default.
- W1979704228 creator A5031880803 @default.
- W1979704228 creator A5050076194 @default.
- W1979704228 creator A5074442133 @default.
- W1979704228 creator A5079040921 @default.
- W1979704228 creator A5079875502 @default.
- W1979704228 creator A5082587732 @default.
- W1979704228 creator A5089863634 @default.
- W1979704228 date "2006-01-01" @default.
- W1979704228 modified "2023-10-17" @default.
- W1979704228 title "Expression of Tumor-Associated Differentially Expressed Gene-14 <i>(TADG-14/KLK8)</i> and Its Protein hK8 in Uterine Endometria and Endometrial Carcinomas" @default.
- W1979704228 cites W143584593 @default.
- W1979704228 cites W1508240107 @default.
- W1979704228 cites W1935076655 @default.
- W1979704228 cites W1966358964 @default.
- W1979704228 cites W1972581901 @default.
- W1979704228 cites W1973484737 @default.
- W1979704228 cites W1974861755 @default.
- W1979704228 cites W1996532820 @default.
- W1979704228 cites W2000613026 @default.
- W1979704228 cites W2012139965 @default.
- W1979704228 cites W2020785470 @default.
- W1979704228 cites W2024066414 @default.
- W1979704228 cites W2026151657 @default.
- W1979704228 cites W2035437870 @default.
- W1979704228 cites W2038372720 @default.
- W1979704228 cites W2039920498 @default.
- W1979704228 cites W2052593722 @default.
- W1979704228 cites W2054759595 @default.
- W1979704228 cites W2063145549 @default.
- W1979704228 cites W2065855144 @default.
- W1979704228 cites W2065877726 @default.
- W1979704228 cites W2070492192 @default.
- W1979704228 cites W2075744249 @default.
- W1979704228 cites W2084608619 @default.
- W1979704228 cites W2089390907 @default.
- W1979704228 cites W2090283697 @default.
- W1979704228 cites W2110337690 @default.
- W1979704228 cites W2112343680 @default.
- W1979704228 cites W2114286587 @default.
- W1979704228 cites W2116586212 @default.
- W1979704228 cites W2119408931 @default.
- W1979704228 cites W2123725304 @default.
- W1979704228 cites W2123856998 @default.
- W1979704228 cites W2133563508 @default.
- W1979704228 cites W2136010983 @default.
- W1979704228 cites W2141368094 @default.
- W1979704228 cites W2146501048 @default.
- W1979704228 cites W2153569860 @default.
- W1979704228 cites W2187627689 @default.
- W1979704228 doi "https://doi.org/10.1159/000094741" @default.
- W1979704228 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16888409" @default.
- W1979704228 hasPublicationYear "2006" @default.
- W1979704228 type Work @default.
- W1979704228 sameAs 1979704228 @default.
- W1979704228 citedByCount "17" @default.
- W1979704228 countsByYear W19797042282012 @default.
- W1979704228 countsByYear W19797042282013 @default.
- W1979704228 countsByYear W19797042282014 @default.
- W1979704228 countsByYear W19797042282018 @default.
- W1979704228 countsByYear W19797042282019 @default.
- W1979704228 countsByYear W19797042282023 @default.
- W1979704228 crossrefType "journal-article" @default.
- W1979704228 hasAuthorship W1979704228A5012949887 @default.
- W1979704228 hasAuthorship W1979704228A5024093607 @default.
- W1979704228 hasAuthorship W1979704228A5031880803 @default.
- W1979704228 hasAuthorship W1979704228A5050076194 @default.
- W1979704228 hasAuthorship W1979704228A5074442133 @default.
- W1979704228 hasAuthorship W1979704228A5079040921 @default.
- W1979704228 hasAuthorship W1979704228A5079875502 @default.
- W1979704228 hasAuthorship W1979704228A5082587732 @default.
- W1979704228 hasAuthorship W1979704228A5089863634 @default.
- W1979704228 hasConcept C121608353 @default.
- W1979704228 hasConcept C126322002 @default.
- W1979704228 hasConcept C134018914 @default.
- W1979704228 hasConcept C16685009 @default.
- W1979704228 hasConcept C204232928 @default.
- W1979704228 hasConcept C2777088508 @default.
- W1979704228 hasConcept C2777546739 @default.
- W1979704228 hasConcept C2779742232 @default.
- W1979704228 hasConcept C2781197716 @default.
- W1979704228 hasConcept C55493867 @default.
- W1979704228 hasConcept C555283112 @default.
- W1979704228 hasConcept C71924100 @default.
- W1979704228 hasConcept C86803240 @default.
- W1979704228 hasConceptScore W1979704228C121608353 @default.
- W1979704228 hasConceptScore W1979704228C126322002 @default.
- W1979704228 hasConceptScore W1979704228C134018914 @default.
- W1979704228 hasConceptScore W1979704228C16685009 @default.
- W1979704228 hasConceptScore W1979704228C204232928 @default.
- W1979704228 hasConceptScore W1979704228C2777088508 @default.
- W1979704228 hasConceptScore W1979704228C2777546739 @default.
- W1979704228 hasConceptScore W1979704228C2779742232 @default.
- W1979704228 hasConceptScore W1979704228C2781197716 @default.
- W1979704228 hasConceptScore W1979704228C55493867 @default.