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- W1979782739 abstract "Bioactivity-directed fractionation led to the isolation of two new 7-dehydroaporphine alkaloids, 7-hydroxy-dehydrothalicsimidine (1) and 7-formyl-dehydrothalicsimidine (2), along with the five known alkaloids, thalicsimidine (3), norpurpureine (4), N-methyllaurotetanine (5), lirinidine (6) and N-methylasimilobine (7), from the leaves of Annona purpurea. Structural elucidation of these compounds was established by mass and spectroscopic analyses. Among them, 1, 3, 4, 6 and 7 exhibited significant inhibition of collagen, arachidonic acid and platelet activating factor-induced platelet aggregation; 1 also showed inhibition against thrombin-induced platelet aggregation." @default.
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- W1979782739 date "1998-12-01" @default.
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- W1979782739 title "Two new 7-dehydroaporphine alkaloids and antiplatelet action aporphines from the leaves of Annona purpurea" @default.
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- W1979782739 doi "https://doi.org/10.1016/s0031-9422(98)00376-8" @default.
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