Matches in SemOpenAlex for { <https://semopenalex.org/work/W1979787578> ?p ?o ?g. }
- W1979787578 endingPage "35" @default.
- W1979787578 startingPage "29" @default.
- W1979787578 abstract "The purpose of the present study was to evaluate in vivo the effect of a non competitive antagonist of the NMDA receptor, eliprodil, on the size of a focal ischaemic insult and on its temporal evolution in a rat model, using a spin-echo diffusion magnetic resonance imaging multislice technique. Rats were either injected with 1 mg/kg i.v. of eliprodil or with the vehicle only (placebo) 5 min after middle cerebral artery occlusion, or not injected (controls). Ten coronal slices were acquired every hour, up to 7 h after occlusion of the artery, and the volume of hyperintense signals was measured at each time point and for each animal. Diffusion magnetic resonance images revealed that the administration of eliprodil reduced significantly (by 50% or more) the volume of ischaemia, up to 7 h after occlusion, particularly in the cortex of the ipsilateral hemisphere. The results show the potential efficacy of eliprodil to reduce the cerebral ischaemic volume after arterial occlusion, thus confirming the interest of glutamate receptor antagonists in the treatment of ischaemia." @default.
- W1979787578 created "2016-06-24" @default.
- W1979787578 creator A5005570300 @default.
- W1979787578 creator A5013238155 @default.
- W1979787578 creator A5019149513 @default.
- W1979787578 creator A5039037904 @default.
- W1979787578 creator A5078707630 @default.
- W1979787578 creator A5082716685 @default.
- W1979787578 date "1998-07-01" @default.
- W1979787578 modified "2023-09-27" @default.
- W1979787578 title "The effect of eliprodil on the evolution of a focal cerebral ischaemia in vivo" @default.
- W1979787578 cites W1964915869 @default.
- W1979787578 cites W1967573213 @default.
- W1979787578 cites W1967913693 @default.
- W1979787578 cites W1970231623 @default.
- W1979787578 cites W1977543906 @default.
- W1979787578 cites W1996426651 @default.
- W1979787578 cites W1997694194 @default.
- W1979787578 cites W2001198148 @default.
- W1979787578 cites W2002264129 @default.
- W1979787578 cites W2008084882 @default.
- W1979787578 cites W2010110373 @default.
- W1979787578 cites W2011132353 @default.
- W1979787578 cites W2015308817 @default.
- W1979787578 cites W2015830672 @default.
- W1979787578 cites W2018592951 @default.
- W1979787578 cites W2020622209 @default.
- W1979787578 cites W2022593257 @default.
- W1979787578 cites W2031702150 @default.
- W1979787578 cites W2043151182 @default.
- W1979787578 cites W2053068374 @default.
- W1979787578 cites W2065393358 @default.
- W1979787578 cites W2076060467 @default.
- W1979787578 cites W2078307237 @default.
- W1979787578 cites W2085483711 @default.
- W1979787578 cites W2089637422 @default.
- W1979787578 cites W2095285055 @default.
- W1979787578 cites W2116713505 @default.
- W1979787578 cites W2143773297 @default.
- W1979787578 cites W2144430198 @default.
- W1979787578 cites W2152991303 @default.
- W1979787578 cites W2432562135 @default.
- W1979787578 cites W66689890 @default.
- W1979787578 doi "https://doi.org/10.1016/s0014-2999(98)00330-6" @default.
- W1979787578 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9718264" @default.
- W1979787578 hasPublicationYear "1998" @default.
- W1979787578 type Work @default.
- W1979787578 sameAs 1979787578 @default.
- W1979787578 citedByCount "7" @default.
- W1979787578 countsByYear W19797875782014 @default.
- W1979787578 countsByYear W19797875782017 @default.
- W1979787578 countsByYear W19797875782023 @default.
- W1979787578 crossrefType "journal-article" @default.
- W1979787578 hasAuthorship W1979787578A5005570300 @default.
- W1979787578 hasAuthorship W1979787578A5013238155 @default.
- W1979787578 hasAuthorship W1979787578A5019149513 @default.
- W1979787578 hasAuthorship W1979787578A5039037904 @default.
- W1979787578 hasAuthorship W1979787578A5078707630 @default.
- W1979787578 hasAuthorship W1979787578A5082716685 @default.
- W1979787578 hasConcept C126322002 @default.
- W1979787578 hasConcept C126838900 @default.
- W1979787578 hasConcept C143409427 @default.
- W1979787578 hasConcept C150903083 @default.
- W1979787578 hasConcept C15744967 @default.
- W1979787578 hasConcept C169760540 @default.
- W1979787578 hasConcept C170493617 @default.
- W1979787578 hasConcept C207001950 @default.
- W1979787578 hasConcept C2776268601 @default.
- W1979787578 hasConcept C2776885963 @default.
- W1979787578 hasConcept C541997718 @default.
- W1979787578 hasConcept C61174792 @default.
- W1979787578 hasConcept C67018056 @default.
- W1979787578 hasConcept C71924100 @default.
- W1979787578 hasConcept C86803240 @default.
- W1979787578 hasConceptScore W1979787578C126322002 @default.
- W1979787578 hasConceptScore W1979787578C126838900 @default.
- W1979787578 hasConceptScore W1979787578C143409427 @default.
- W1979787578 hasConceptScore W1979787578C150903083 @default.
- W1979787578 hasConceptScore W1979787578C15744967 @default.
- W1979787578 hasConceptScore W1979787578C169760540 @default.
- W1979787578 hasConceptScore W1979787578C170493617 @default.
- W1979787578 hasConceptScore W1979787578C207001950 @default.
- W1979787578 hasConceptScore W1979787578C2776268601 @default.
- W1979787578 hasConceptScore W1979787578C2776885963 @default.
- W1979787578 hasConceptScore W1979787578C541997718 @default.
- W1979787578 hasConceptScore W1979787578C61174792 @default.
- W1979787578 hasConceptScore W1979787578C67018056 @default.
- W1979787578 hasConceptScore W1979787578C71924100 @default.
- W1979787578 hasConceptScore W1979787578C86803240 @default.
- W1979787578 hasIssue "1" @default.
- W1979787578 hasLocation W19797875781 @default.
- W1979787578 hasLocation W19797875782 @default.
- W1979787578 hasOpenAccess W1979787578 @default.
- W1979787578 hasPrimaryLocation W19797875781 @default.
- W1979787578 hasRelatedWork W126933829 @default.
- W1979787578 hasRelatedWork W1988253755 @default.
- W1979787578 hasRelatedWork W1996664884 @default.
- W1979787578 hasRelatedWork W2032398953 @default.