FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1979793530> ?p ?o ?g. }

• W1979793530 endingPage "14" @default.
• W1979793530 startingPage "8" @default.
• W1979793530 abstract "Our experience with amiodarone therapy in 145 consecutively referred patients with medically refractory sustained ventricular tachycardia and/or fibrillation treated for at least 3 years was reviewed. Ninety-seven had sustained ventricular tachycardia; the remaining 48 patients were survivors of sudden cardiac death. The patients had a mean of 3.7±1.4 unsuccessful anti-arrhythmic drug trials before initiation of amiodarone. The initial doses of amiodarone averaged 845±258 mg for the first 2 weeks and 56% of all patients received a type 1 antiarrhythmic drug in addition to amiodarone during the initial phase of therapy. The average maintenance dose of amiodarone was 410±187 mg per day. All patients were followed for a minimum of 3 years or until death or withdrawal from therapy. The maximum follow-up was a period of 8 years. Thus, the average duration of amiodarone therapy was 39±26 months, representing 472 patient years of therapeutic time on amiodarone. The incidence of deaths either caused by a documented ventricular tachyarrhythmia or presumed to result from an arrhythmic cause was 5.5% in the first year and 3.4% in each of the second and third years of follow-up. During the entire period of follow-up, 56 patients died of all causes (38.6% of the study population). Survival over the follow-up period was influenced significantly by left ventricular function, as judged by either New York Heart Association Functional Class or objective assessment of left ventricular ejection fraction, which was available in 102 patients. Seventeen percent of the patients had to be withdrawn from the study because of side effects to amiodarone, including 6% caused by pulmonary toxicity. In summary, we have found amiodarone to be highly effective in prophylaxis of arrhythmic deaths in a high-risk population of patients referred for refractory life-threatening ventricular arrhythmias. The observed incidence of arrhythmic deaths during the minimum follow-up period of 3 years in these 145 patients should be balanced against the withdrawal rate of 17%, necessitated by side effects from amiodarone." @default.
• W1979793530 created "2016-06-24" @default.
• W1979793530 creator A5002304356 @default.
• W1979793530 creator A5007342848 @default.
• W1979793530 creator A5015803414 @default.
• W1979793530 creator A5019273492 @default.
• W1979793530 creator A5066684978 @default.
• W1979793530 creator A5067751284 @default.
• W1979793530 creator A5089187739 @default.
• W1979793530 date "1990-01-01" @default.
• W1979793530 modified "2023-09-25" @default.
• W1979793530 title "Benefit and risks of long-term amiodarone therapy for sustained ventricular tachycardia/fibrillation: Minimum of three-year follow-up in 145 patients" @default.
• W1979793530 cites W1970527602 @default.
• W1979793530 cites W1972185067 @default.
• W1979793530 cites W1976055925 @default.
• W1979793530 cites W1979418870 @default.
• W1979793530 cites W1980668891 @default.
• W1979793530 cites W1994640924 @default.
• W1979793530 cites W2002965836 @default.
• W1979793530 cites W2025189891 @default.
• W1979793530 cites W2039937506 @default.
• W1979793530 cites W2041069426 @default.
• W1979793530 cites W2058755860 @default.
• W1979793530 cites W2071867881 @default.
• W1979793530 cites W2077014760 @default.
• W1979793530 cites W2078754141 @default.
• W1979793530 cites W2081090151 @default.
• W1979793530 cites W2081732894 @default.
• W1979793530 cites W2092357214 @default.
• W1979793530 cites W2100069431 @default.
• W1979793530 cites W2131312586 @default.
• W1979793530 doi "https://doi.org/10.1016/s0002-8703(05)80074-2" @default.
• W1979793530 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2296879" @default.
• W1979793530 hasPublicationYear "1990" @default.
• W1979793530 type Work @default.
• W1979793530 sameAs 1979793530 @default.
• W1979793530 citedByCount "33" @default.
• W1979793530 crossrefType "journal-article" @default.
• W1979793530 hasAuthorship W1979793530A5002304356 @default.
• W1979793530 hasAuthorship W1979793530A5007342848 @default.
• W1979793530 hasAuthorship W1979793530A5015803414 @default.
• W1979793530 hasAuthorship W1979793530A5019273492 @default.
• W1979793530 hasAuthorship W1979793530A5066684978 @default.
• W1979793530 hasAuthorship W1979793530A5067751284 @default.
• W1979793530 hasAuthorship W1979793530A5089187739 @default.
• W1979793530 hasConcept C121332964 @default.
• W1979793530 hasConcept C126322002 @default.
• W1979793530 hasConcept C142424586 @default.
• W1979793530 hasConcept C164705383 @default.
• W1979793530 hasConcept C2776331378 @default.
• W1979793530 hasConcept C2778094803 @default.
• W1979793530 hasConcept C2778198053 @default.
• W1979793530 hasConcept C2779161974 @default.
• W1979793530 hasConcept C2780283014 @default.
• W1979793530 hasConcept C2781005686 @default.
• W1979793530 hasConcept C2908647359 @default.
• W1979793530 hasConcept C2993353509 @default.
• W1979793530 hasConcept C42219234 @default.
• W1979793530 hasConcept C71924100 @default.
• W1979793530 hasConcept C78085059 @default.
• W1979793530 hasConcept C87355193 @default.
• W1979793530 hasConcept C99454951 @default.
• W1979793530 hasConceptScore W1979793530C121332964 @default.
• W1979793530 hasConceptScore W1979793530C126322002 @default.
• W1979793530 hasConceptScore W1979793530C142424586 @default.
• W1979793530 hasConceptScore W1979793530C164705383 @default.
• W1979793530 hasConceptScore W1979793530C2776331378 @default.
• W1979793530 hasConceptScore W1979793530C2778094803 @default.
• W1979793530 hasConceptScore W1979793530C2778198053 @default.
• W1979793530 hasConceptScore W1979793530C2779161974 @default.
• W1979793530 hasConceptScore W1979793530C2780283014 @default.
• W1979793530 hasConceptScore W1979793530C2781005686 @default.
• W1979793530 hasConceptScore W1979793530C2908647359 @default.
• W1979793530 hasConceptScore W1979793530C2993353509 @default.
• W1979793530 hasConceptScore W1979793530C42219234 @default.
• W1979793530 hasConceptScore W1979793530C71924100 @default.
• W1979793530 hasConceptScore W1979793530C78085059 @default.
• W1979793530 hasConceptScore W1979793530C87355193 @default.
• W1979793530 hasConceptScore W1979793530C99454951 @default.
• W1979793530 hasIssue "1" @default.
• W1979793530 hasLocation W19797935301 @default.
• W1979793530 hasLocation W19797935302 @default.
• W1979793530 hasOpenAccess W1979793530 @default.
• W1979793530 hasPrimaryLocation W19797935301 @default.
• W1979793530 hasRelatedWork W2001421296 @default.
• W1979793530 hasRelatedWork W2009378781 @default.
• W1979793530 hasRelatedWork W2034363986 @default.
• W1979793530 hasRelatedWork W2043337132 @default.
• W1979793530 hasRelatedWork W2078400500 @default.
• W1979793530 hasRelatedWork W2092852056 @default.
• W1979793530 hasRelatedWork W2131262499 @default.
• W1979793530 hasRelatedWork W2146728836 @default.
• W1979793530 hasRelatedWork W2416475623 @default.
• W1979793530 hasRelatedWork W4213191135 @default.
• W1979793530 hasVolume "119" @default.
• W1979793530 isParatext "false" @default.
• W1979793530 isRetracted "false" @default.
• W1979793530 magId "1979793530" @default.

• next