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- W1979796759 abstract "Comparative pathological effects in three species of fish and six species of invertebrates were investigated using a chemically contaminated sediment from Black Rock Harbor (BRH), Connecticut, USA. Substances contained in BRH sediment are known to be genotoxic, carcinogenic, co-carcinogenic and tumor-promoting. Proliferative lesions were observed in winter flounder (Pseudopleuronectes americanus) external, oral and esophageal epithelial surfaces, renal vascular and nephroblastic elements, and the pancreatic islets. Islet lesions included cystic adenomas and a diffuse islet proliferative condition, nesidioblastosis. In addition, pathology was enhanced when winter flounder were fed mussels (Mytilus edulis) previously exposed to BRH sediment. Neoplastic lesions developed in kidney tubule epithelia, gills, some regions of the gastrointestinal tract, neural elements and heart of oysters (Crassostrea virginica) exposed to BRH sediment for 30 days in the laboratory. In addition, renal carcinomas in three oysters had metastasized to the viseral ganglion. Lesions were also found in oysters exposed in situ in BRH and Long Island Sound for 30 or 36 days. Digestive diverticula, gills and kidneys appeared to be the prime organs affected in mussels, soft-shelled clams (Mya arenaria) and oysters exposed to BRH sediment. Mucous cell activity increased greatly in corals (Astrangia densa) while no microscopic lesions were detectable in lobster (Homarus americanus) exposed in the laboratory. Myxomas were also found in the hearts of < 5% of the mussels exposed in the laboratory." @default.
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- W1979796759 date "1988-01-01" @default.
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- W1979796759 title "Comparative histopathological effects of chemically contaminated sediment on marine organisms" @default.
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- W1979796759 doi "https://doi.org/10.1016/0141-1136(88)90327-3" @default.
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