FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1979805199> ?p ?o ?g. }

• W1979805199 endingPage "47" @default.
• W1979805199 startingPage "39" @default.
• W1979805199 abstract "Fenretinide and tamoxifen have additive antitumor effects preclinically. We performed a randomized, placebo-controlled, double-blind adjuvant trial in breast cancer patients treated for 5 years with tamoxifen, with or without fenretinide. Between October 1995 and October 1999, 426 postmenopausal women with hormone receptor-positive breast cancer were randomized. Patients were monitored for efficacy and toxicity. Four hundred and nineteen patients were evaluable. The study was terminated early due to slow accrual. There were no significant differences between treatment groups in DFS, TTR or survival. More patients stopped treatment early on the fenretinide arm than on placebo (P = 0.02). Grade 3/4 toxicities, including visual problems and musculoskeletal complaints were more common in patients receiving fenretinide (P = 0.007). A Night Blindness Questionnaire was used to monitor nyctalopia, which was slightly, but not significantly, more common on fenretinide. In this underpowered study, no significant difference was observed in efficacy between treatment groups. This trial provides important toxicity information about fenretinide, a retinoid that has been used in the prevention setting, because it is the only placebo-controlled, double-blind randomized study ever performed." @default.
• W1979805199 created "2016-06-24" @default.
• W1979805199 creator A5002841636 @default.
• W1979805199 creator A5013631740 @default.
• W1979805199 creator A5030358067 @default.
• W1979805199 creator A5030476275 @default.
• W1979805199 creator A5039225060 @default.
• W1979805199 creator A5043219897 @default.
• W1979805199 creator A5047039049 @default.
• W1979805199 creator A5078129443 @default.
• W1979805199 creator A5083904553 @default.
• W1979805199 date "2010-09-28" @default.
• W1979805199 modified "2023-09-23" @default.
• W1979805199 title "Phase III double-blind, placebo-controlled, prospective randomized trial of adjuvant tamoxifen vs. tamoxifen and fenretinide in postmenopausal women with positive receptors (EB193): an intergroup trial coordinated by the Eastern Cooperative Oncology Group" @default.
• W1979805199 cites W1562190372 @default.
• W1979805199 cites W1969965083 @default.
• W1979805199 cites W1972468918 @default.
• W1979805199 cites W2013171114 @default.
• W1979805199 cites W2023044430 @default.
• W1979805199 cites W2056444389 @default.
• W1979805199 cites W2056799839 @default.
• W1979805199 cites W2085901559 @default.
• W1979805199 cites W2094325227 @default.
• W1979805199 cites W2099089851 @default.
• W1979805199 cites W2109568316 @default.
• W1979805199 cites W2117350664 @default.
• W1979805199 cites W2152240177 @default.
• W1979805199 cites W2154015002 @default.
• W1979805199 cites W2157226695 @default.
• W1979805199 cites W2226738742 @default.
• W1979805199 cites W2228077492 @default.
• W1979805199 cites W2460191037 @default.
• W1979805199 cites W3041047318 @default.
• W1979805199 doi "https://doi.org/10.1007/s12032-010-9682-1" @default.
• W1979805199 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4947231" @default.
• W1979805199 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20878269" @default.
• W1979805199 hasPublicationYear "2010" @default.
• W1979805199 type Work @default.
• W1979805199 sameAs 1979805199 @default.
• W1979805199 citedByCount "15" @default.
• W1979805199 countsByYear W19798051992013 @default.
• W1979805199 countsByYear W19798051992015 @default.
• W1979805199 countsByYear W19798051992017 @default.
• W1979805199 countsByYear W19798051992018 @default.
• W1979805199 countsByYear W19798051992019 @default.
• W1979805199 countsByYear W19798051992020 @default.
• W1979805199 countsByYear W19798051992021 @default.
• W1979805199 countsByYear W19798051992022 @default.
• W1979805199 countsByYear W19798051992023 @default.
• W1979805199 crossrefType "journal-article" @default.
• W1979805199 hasAuthorship W1979805199A5002841636 @default.
• W1979805199 hasAuthorship W1979805199A5013631740 @default.
• W1979805199 hasAuthorship W1979805199A5030358067 @default.
• W1979805199 hasAuthorship W1979805199A5030476275 @default.
• W1979805199 hasAuthorship W1979805199A5039225060 @default.
• W1979805199 hasAuthorship W1979805199A5043219897 @default.
• W1979805199 hasAuthorship W1979805199A5047039049 @default.
• W1979805199 hasAuthorship W1979805199A5078129443 @default.
• W1979805199 hasAuthorship W1979805199A5083904553 @default.
• W1979805199 hasBestOaLocation W19798051992 @default.
• W1979805199 hasConcept C104317684 @default.
• W1979805199 hasConcept C121608353 @default.
• W1979805199 hasConcept C126322002 @default.
• W1979805199 hasConcept C142724271 @default.
• W1979805199 hasConcept C143998085 @default.
• W1979805199 hasConcept C168563851 @default.
• W1979805199 hasConcept C185592680 @default.
• W1979805199 hasConcept C204787440 @default.
• W1979805199 hasConcept C27081682 @default.
• W1979805199 hasConcept C2775954498 @default.
• W1979805199 hasConcept C2777176818 @default.
• W1979805199 hasConcept C2780533455 @default.
• W1979805199 hasConcept C2781121885 @default.
• W1979805199 hasConcept C530470458 @default.
• W1979805199 hasConcept C55493867 @default.
• W1979805199 hasConcept C71924100 @default.
• W1979805199 hasConcept C90924648 @default.
• W1979805199 hasConceptScore W1979805199C104317684 @default.
• W1979805199 hasConceptScore W1979805199C121608353 @default.
• W1979805199 hasConceptScore W1979805199C126322002 @default.
• W1979805199 hasConceptScore W1979805199C142724271 @default.
• W1979805199 hasConceptScore W1979805199C143998085 @default.
• W1979805199 hasConceptScore W1979805199C168563851 @default.
• W1979805199 hasConceptScore W1979805199C185592680 @default.
• W1979805199 hasConceptScore W1979805199C204787440 @default.
• W1979805199 hasConceptScore W1979805199C27081682 @default.
• W1979805199 hasConceptScore W1979805199C2775954498 @default.
• W1979805199 hasConceptScore W1979805199C2777176818 @default.
• W1979805199 hasConceptScore W1979805199C2780533455 @default.
• W1979805199 hasConceptScore W1979805199C2781121885 @default.
• W1979805199 hasConceptScore W1979805199C530470458 @default.
• W1979805199 hasConceptScore W1979805199C55493867 @default.
• W1979805199 hasConceptScore W1979805199C71924100 @default.
• W1979805199 hasConceptScore W1979805199C90924648 @default.
• W1979805199 hasIssue "S1" @default.
• W1979805199 hasLocation W19798051991 @default.
• W1979805199 hasLocation W19798051992 @default.
• W1979805199 hasLocation W19798051993 @default.

• next