FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1979818116> ?p ?o ?g. }

• W1979818116 endingPage "689" @default.
• W1979818116 startingPage "682" @default.
• W1979818116 abstract "Few studies have characterized the regional scale (300-500 km) variability of the mutagenicity of respirable airborne particles (PM2.5). We previously collected 24-h PM2.5 samples for 1 year from background, suburban, and urban sites in Massachusetts (MA) and rural and urban sites in upstate New York (NY) (n = 53-60 samples per site). Bimonthly composites of these samples were mutagenic to human cells. The present report describes our effort to identify chemical classes responsible for the mutagenicity of the samples, to quantify spatial differences in mutagenicity, and to compare the mutagenicity of samples composited in different ways. Organic extracts and HPLC fractions (two nonpolar, one semipolar, and one polar) of annual composites were tested for mutagenicity in the h1A1v2 cells, a line of human B-lymphoblastoid cells that express cytochrome P450 CYP1A1 cDNA. The mutagenic potency (induced mutant fraction per microg organic carbon) of the semipolarfractions was the highest at all five sites, accounting for 35-82% of total mutagenic potency of the samples, vs the nonpolar (4-38%) and polar (14-32%) fractions. These results are consistent with previous studies. While unfractionated extracts exhibited no spatial variations, the mutagenicity of semipolar fractions at the NY sites was approximately 2-fold higher than at the MA sites. This suggests there may be significant regional differences in the sources and/ or transport and transformation of mutagenic compounds in PM2.5. In addition, mutagenic potency was sensitive to whether samples were fractionated and how they were composited: unfractionated annual composite samples at the NY sites were significantly less mutagenic than their semipolar fractions and the annual average of bimonthly composites; spatial differences in the mutagenic potency of bimonthly composites and the semipolar fractions were not apparent in the annual composites." @default.
• W1979818116 created "2016-06-24" @default.
• W1979818116 creator A5017257889 @default.
• W1979818116 creator A5023776289 @default.
• W1979818116 creator A5031376447 @default.
• W1979818116 creator A5043987858 @default.
• W1979818116 creator A5047139559 @default.
• W1979818116 creator A5076608688 @default.
• W1979818116 creator A5088332392 @default.
• W1979818116 date "2003-12-12" @default.
• W1979818116 modified "2023-10-12" @default.
• W1979818116 title "Human-Cell Mutagens in Respirable Airborne Particles in the Northeastern United States. 1. Mutagenicity of Fractionated Samples" @default.
• W1979818116 cites W1553497241 @default.
• W1979818116 cites W1575020943 @default.
• W1979818116 cites W1970793782 @default.
• W1979818116 cites W1994615418 @default.
• W1979818116 cites W1995163927 @default.
• W1979818116 cites W1999293112 @default.
• W1979818116 cites W2004231236 @default.
• W1979818116 cites W2006856983 @default.
• W1979818116 cites W2009324260 @default.
• W1979818116 cites W2009433300 @default.
• W1979818116 cites W2014793084 @default.
• W1979818116 cites W2024852749 @default.
• W1979818116 cites W2028468091 @default.
• W1979818116 cites W2035827113 @default.
• W1979818116 cites W2041045166 @default.
• W1979818116 cites W2050181450 @default.
• W1979818116 cites W2058544607 @default.
• W1979818116 cites W2060434834 @default.
• W1979818116 cites W2061778686 @default.
• W1979818116 cites W2062360746 @default.
• W1979818116 cites W2068701432 @default.
• W1979818116 cites W2073353075 @default.
• W1979818116 cites W2074912117 @default.
• W1979818116 cites W2075163812 @default.
• W1979818116 cites W2075516925 @default.
• W1979818116 cites W2083441497 @default.
• W1979818116 cites W2085746473 @default.
• W1979818116 cites W2091124922 @default.
• W1979818116 cites W2092300766 @default.
• W1979818116 cites W2092626706 @default.
• W1979818116 cites W2116130499 @default.
• W1979818116 cites W2122939933 @default.
• W1979818116 cites W2124766406 @default.
• W1979818116 cites W2141390733 @default.
• W1979818116 cites W2318698569 @default.
• W1979818116 cites W74144201 @default.
• W1979818116 doi "https://doi.org/10.1021/es0347282" @default.
• W1979818116 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14968851" @default.
• W1979818116 hasPublicationYear "2003" @default.
• W1979818116 type Work @default.
• W1979818116 sameAs 1979818116 @default.
• W1979818116 citedByCount "69" @default.
• W1979818116 countsByYear W19798181162012 @default.
• W1979818116 countsByYear W19798181162013 @default.
• W1979818116 countsByYear W19798181162014 @default.
• W1979818116 countsByYear W19798181162015 @default.
• W1979818116 countsByYear W19798181162016 @default.
• W1979818116 countsByYear W19798181162017 @default.
• W1979818116 countsByYear W19798181162018 @default.
• W1979818116 countsByYear W19798181162019 @default.
• W1979818116 countsByYear W19798181162020 @default.
• W1979818116 countsByYear W19798181162021 @default.
• W1979818116 countsByYear W19798181162022 @default.
• W1979818116 countsByYear W19798181162023 @default.
• W1979818116 crossrefType "journal-article" @default.
• W1979818116 hasAuthorship W1979818116A5017257889 @default.
• W1979818116 hasAuthorship W1979818116A5023776289 @default.
• W1979818116 hasAuthorship W1979818116A5031376447 @default.
• W1979818116 hasAuthorship W1979818116A5043987858 @default.
• W1979818116 hasAuthorship W1979818116A5047139559 @default.
• W1979818116 hasAuthorship W1979818116A5076608688 @default.
• W1979818116 hasAuthorship W1979818116A5088332392 @default.
• W1979818116 hasConcept C107872376 @default.
• W1979818116 hasConcept C185592680 @default.
• W1979818116 hasConcept C202751555 @default.
• W1979818116 hasConcept C2776639595 @default.
• W1979818116 hasConcept C552990157 @default.
• W1979818116 hasConcept C55493867 @default.
• W1979818116 hasConcept C57992300 @default.
• W1979818116 hasConceptScore W1979818116C107872376 @default.
• W1979818116 hasConceptScore W1979818116C185592680 @default.
• W1979818116 hasConceptScore W1979818116C202751555 @default.
• W1979818116 hasConceptScore W1979818116C2776639595 @default.
• W1979818116 hasConceptScore W1979818116C552990157 @default.
• W1979818116 hasConceptScore W1979818116C55493867 @default.
• W1979818116 hasConceptScore W1979818116C57992300 @default.
• W1979818116 hasIssue "3" @default.
• W1979818116 hasLocation W19798181161 @default.
• W1979818116 hasLocation W19798181162 @default.
• W1979818116 hasOpenAccess W1979818116 @default.
• W1979818116 hasPrimaryLocation W19798181161 @default.
• W1979818116 hasRelatedWork W1531601525 @default.
• W1979818116 hasRelatedWork W2319480705 @default.
• W1979818116 hasRelatedWork W2384464875 @default.
• W1979818116 hasRelatedWork W2606230654 @default.
• W1979818116 hasRelatedWork W2607424097 @default.

• next