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- W1979896871 abstract "Abstract 1. 1. The epidermal cap of the regenerating forelimb of larval Amblystoma was induced to become eccentrically located at the posterior border of the amputation surface by means of a skin excision ( 1 2 mm long by 1 3 mm wide) at the posterior edge of the amputation surface. Healing of the skin excision wound by epidermal migration, particularly from the epidermis covering the amputation surface, carried the epidermal cap to the postaxial border of the limb tip. 2. 2. Blastermal cells aggregated beneath the eccentric epidermal cap to form a correspondingly eccentric blastema which developed into an asymmetrical regenerate. 3. 3. Eccentric epidermal caps were induced in regressed limbs after all limb tissues had completely dedifferentiated. Blastemal cells aggregated beneath the eccentric epidermal caps to produce eccentric blastemata and regenerates. Thus the eccentric epidermal cap induced a corresponding eccentricity of regenerative outgrowth not by a differential histolysis of limb tissues, but by controlling the aggregation of blastemal cells." @default.
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- W1979896871 date "1960-12-01" @default.
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- W1979896871 title "Influence of an eccentric epidermal cap on limb regeneration in Amblystoma larvae" @default.
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- W1979896871 doi "https://doi.org/10.1016/0012-1606(60)90054-3" @default.
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