Matches in SemOpenAlex for { <https://semopenalex.org/work/W1979921554> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W1979921554 abstract "A derivative of phencyclidine (PCP, 1 in fig. 1) bearing an isothiocyanate moiety on the meta position of the aromatic ring (Metaphit, 3 in fig. 1) has been synthesized and identified as a rapid and specific site-directed acylating agent of the [3H]phencyclidine binding site in rat brain homogenates. The percentage of sites irreversibly inactivated by Metaphit was found to be the same in the hippocampus and striatum and the remaining sites were unaffected by Metaphit treatment under any conditions, suggesting that at least two distinct binding sites are present. An isomeric isothiocyanate derivative did not irreversibly inhibit [3H]phencyclidine receptors, indicating structural specificity for Metaphit in the inhibition of these receptors. The availability of Metaphit should greatly facilitate study of the structure and function of the phencyclidine receptors." @default.
- W1979921554 created "2016-06-24" @default.
- W1979921554 creator A5003796530 @default.
- W1979921554 creator A5007922126 @default.
- W1979921554 creator A5039818306 @default.
- W1979921554 creator A5072565784 @default.
- W1979921554 date "1985-02-25" @default.
- W1979921554 modified "2023-10-16" @default.
- W1979921554 title "A specific acylating agent for the [3 H]phencyclidine receptors in rat brain" @default.
- W1979921554 cites W1964023889 @default.
- W1979921554 cites W1969313040 @default.
- W1979921554 cites W1989572166 @default.
- W1979921554 cites W2012415100 @default.
- W1979921554 cites W2028012756 @default.
- W1979921554 cites W2043813981 @default.
- W1979921554 cites W2058003673 @default.
- W1979921554 cites W2070182120 @default.
- W1979921554 cites W2071909892 @default.
- W1979921554 cites W2072526170 @default.
- W1979921554 cites W2078763659 @default.
- W1979921554 cites W2084536694 @default.
- W1979921554 cites W2088330044 @default.
- W1979921554 cites W2089327645 @default.
- W1979921554 cites W2089461595 @default.
- W1979921554 cites W2094557023 @default.
- W1979921554 cites W2115250531 @default.
- W1979921554 cites W2949454629 @default.
- W1979921554 cites W2010851727 @default.
- W1979921554 doi "https://doi.org/10.1016/0014-5793(85)80284-2" @default.
- W1979921554 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2982662" @default.
- W1979921554 hasPublicationYear "1985" @default.
- W1979921554 type Work @default.
- W1979921554 sameAs 1979921554 @default.
- W1979921554 citedByCount "79" @default.
- W1979921554 countsByYear W19799215542015 @default.
- W1979921554 countsByYear W19799215542020 @default.
- W1979921554 crossrefType "journal-article" @default.
- W1979921554 hasAuthorship W1979921554A5003796530 @default.
- W1979921554 hasAuthorship W1979921554A5007922126 @default.
- W1979921554 hasAuthorship W1979921554A5039818306 @default.
- W1979921554 hasAuthorship W1979921554A5072565784 @default.
- W1979921554 hasBestOaLocation W19799215541 @default.
- W1979921554 hasConcept C107824862 @default.
- W1979921554 hasConcept C161790260 @default.
- W1979921554 hasConcept C169760540 @default.
- W1979921554 hasConcept C170493617 @default.
- W1979921554 hasConcept C185592680 @default.
- W1979921554 hasConcept C193557335 @default.
- W1979921554 hasConcept C2776568683 @default.
- W1979921554 hasConcept C2776572452 @default.
- W1979921554 hasConcept C2778851735 @default.
- W1979921554 hasConcept C2780062018 @default.
- W1979921554 hasConcept C513476851 @default.
- W1979921554 hasConcept C55493867 @default.
- W1979921554 hasConcept C67018056 @default.
- W1979921554 hasConcept C71240020 @default.
- W1979921554 hasConcept C86803240 @default.
- W1979921554 hasConcept C98274493 @default.
- W1979921554 hasConceptScore W1979921554C107824862 @default.
- W1979921554 hasConceptScore W1979921554C161790260 @default.
- W1979921554 hasConceptScore W1979921554C169760540 @default.
- W1979921554 hasConceptScore W1979921554C170493617 @default.
- W1979921554 hasConceptScore W1979921554C185592680 @default.
- W1979921554 hasConceptScore W1979921554C193557335 @default.
- W1979921554 hasConceptScore W1979921554C2776568683 @default.
- W1979921554 hasConceptScore W1979921554C2776572452 @default.
- W1979921554 hasConceptScore W1979921554C2778851735 @default.
- W1979921554 hasConceptScore W1979921554C2780062018 @default.
- W1979921554 hasConceptScore W1979921554C513476851 @default.
- W1979921554 hasConceptScore W1979921554C55493867 @default.
- W1979921554 hasConceptScore W1979921554C67018056 @default.
- W1979921554 hasConceptScore W1979921554C71240020 @default.
- W1979921554 hasConceptScore W1979921554C86803240 @default.
- W1979921554 hasConceptScore W1979921554C98274493 @default.
- W1979921554 hasLocation W19799215541 @default.
- W1979921554 hasLocation W19799215542 @default.
- W1979921554 hasOpenAccess W1979921554 @default.
- W1979921554 hasPrimaryLocation W19799215541 @default.
- W1979921554 hasRelatedWork W1965385557 @default.
- W1979921554 hasRelatedWork W1979921554 @default.
- W1979921554 hasRelatedWork W2010672805 @default.
- W1979921554 hasRelatedWork W2011972481 @default.
- W1979921554 hasRelatedWork W2021260741 @default.
- W1979921554 hasRelatedWork W2022837435 @default.
- W1979921554 hasRelatedWork W2057711836 @default.
- W1979921554 hasRelatedWork W2098774754 @default.
- W1979921554 hasRelatedWork W2950119052 @default.
- W1979921554 hasRelatedWork W4220808866 @default.
- W1979921554 isParatext "false" @default.
- W1979921554 isRetracted "false" @default.
- W1979921554 magId "1979921554" @default.
- W1979921554 workType "article" @default.