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- W1979968319 abstract "Septo-optic dysplasia (SOD) is a highly heterogeneous condition comprising variable phenotypes including midline and forebrain abnormalities, optic nerve and pituitary hypoplasia. Most instances of SOD are sporadic and several aetiologies including drug and alcohol abuse have been suggested to account for the pathogenesis of the condition. However, a number of familial cases have been described with an increasing number of mutations in developmental transcription factors including HESX1, SOX2, SOX3 and OTX2 being implicated in its aetiology. These factors are essential for normal forebrain/pituitary development, and disruptions to these genes could account for the features observed in SOD and other midline disorders. The variable phenotypes observed within the condition are most likely due to the varying contributions of genetic and environmental factors. This review will discuss the current knowledge about SOD. Further study of these and other novel factors may shed light on the complex aetiology of this condition." @default.
- W1979968319 created "2016-06-24" @default.
- W1979968319 creator A5025505300 @default.
- W1979968319 creator A5026490084 @default.
- W1979968319 creator A5064729919 @default.
- W1979968319 date "2011-02-01" @default.
- W1979968319 modified "2023-10-03" @default.
- W1979968319 title "Septo-optic dysplasia and other midline defects: The role of transcription factors: HESX1 and beyond" @default.
- W1979968319 cites W1812895422 @default.
- W1979968319 cites W1965752652 @default.
- W1979968319 cites W1969776185 @default.
- W1979968319 cites W1970548028 @default.
- W1979968319 cites W1972555940 @default.
- W1979968319 cites W1977437265 @default.
- W1979968319 cites W1982097990 @default.
- W1979968319 cites W1982438847 @default.
- W1979968319 cites W1988482743 @default.
- W1979968319 cites W1988536370 @default.
- W1979968319 cites W1989108720 @default.
- W1979968319 cites W1992688648 @default.
- W1979968319 cites W1994215160 @default.
- W1979968319 cites W1995442506 @default.
- W1979968319 cites W1995792221 @default.
- W1979968319 cites W1996175571 @default.
- W1979968319 cites W1996258914 @default.
- W1979968319 cites W1998576713 @default.
- W1979968319 cites W2002571981 @default.
- W1979968319 cites W2003051889 @default.
- W1979968319 cites W2006734658 @default.
- W1979968319 cites W2014168492 @default.
- W1979968319 cites W2018216158 @default.
- W1979968319 cites W2021287394 @default.
- W1979968319 cites W2022709759 @default.
- W1979968319 cites W2033806111 @default.
- W1979968319 cites W2036511855 @default.
- W1979968319 cites W2044182000 @default.
- W1979968319 cites W2049324619 @default.
- W1979968319 cites W2050374587 @default.
- W1979968319 cites W205188615 @default.
- W1979968319 cites W2052224954 @default.
- W1979968319 cites W2054287443 @default.
- W1979968319 cites W2062477978 @default.
- W1979968319 cites W2062978858 @default.
- W1979968319 cites W2065482480 @default.
- W1979968319 cites W2069096056 @default.
- W1979968319 cites W2070449844 @default.
- W1979968319 cites W2070697563 @default.
- W1979968319 cites W2074208525 @default.
- W1979968319 cites W2075436572 @default.
- W1979968319 cites W2075452484 @default.
- W1979968319 cites W2076429530 @default.
- W1979968319 cites W2077148578 @default.
- W1979968319 cites W2079816742 @default.
- W1979968319 cites W2082995774 @default.
- W1979968319 cites W2083022446 @default.
- W1979968319 cites W2086502986 @default.
- W1979968319 cites W2086693994 @default.
- W1979968319 cites W2087416500 @default.
- W1979968319 cites W2099140596 @default.
- W1979968319 cites W2099342514 @default.
- W1979968319 cites W2101235427 @default.
- W1979968319 cites W2102342499 @default.
- W1979968319 cites W2104333160 @default.
- W1979968319 cites W2104562814 @default.
- W1979968319 cites W2105691494 @default.
- W1979968319 cites W2111980936 @default.
- W1979968319 cites W2113412178 @default.
- W1979968319 cites W2119657919 @default.
- W1979968319 cites W2120288525 @default.
- W1979968319 cites W2122835820 @default.
- W1979968319 cites W2127510589 @default.
- W1979968319 cites W2129622603 @default.
- W1979968319 cites W2132998555 @default.
- W1979968319 cites W2135676923 @default.
- W1979968319 cites W2142191015 @default.
- W1979968319 cites W2145390828 @default.
- W1979968319 cites W2146813316 @default.
- W1979968319 cites W2148129201 @default.
- W1979968319 cites W2149403398 @default.
- W1979968319 cites W2150105325 @default.
- W1979968319 cites W2151821298 @default.
- W1979968319 cites W2152149172 @default.
- W1979968319 cites W2152909534 @default.
- W1979968319 cites W2164344960 @default.
- W1979968319 cites W2165057755 @default.
- W1979968319 cites W2169438237 @default.
- W1979968319 cites W2169529166 @default.
- W1979968319 cites W2183066763 @default.
- W1979968319 cites W2187208469 @default.
- W1979968319 doi "https://doi.org/10.1016/j.beem.2010.06.008" @default.
- W1979968319 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21396578" @default.
- W1979968319 hasPublicationYear "2011" @default.
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