FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1979969283> ?p ?o ?g. }

• W1979969283 endingPage "851" @default.
• W1979969283 startingPage "845" @default.
• W1979969283 abstract "We report six previously healthy children who several days after a prodromal illness had an acute encephalopathy that ran a biphasic course. It appears to constitute a recognizable syndrome with a good prognosis that can be differentiated from other encephalopathies of obscure origin as previously defined by Lyon et al. The active phase was dominated by coma or confusion and by abnormal movements, including disordered gesticulation and attacks of orofacial dyskinesia or limb dystonia associated with permanent rigidity and culminating in opisthotonic posturing. Repeated seizures were observed in only two patients. Permanent slow waves were recorded on the electroencephalogram in all patients, even during bursts of abnormal movements. Cerebrospinal fluid and results of serologic studies were normal throughout the course of the disease, and attempts at viral isolation and antiviral antibody detection yielded negative results. Brain imaging either showed no abnormalities or suggested a moderate degree of brain edema. The recovery phase, which extended for several weeks, was characterized by a rapid return of motor function and persistent behavioral and cognitive disturbances. Nonverbal reasoning recovered long before verbal expression returned to normal. Four patients eventually recovered fully, whereas two had mild sequelae. We report six previously healthy children who several days after a prodromal illness had an acute encephalopathy that ran a biphasic course. It appears to constitute a recognizable syndrome with a good prognosis that can be differentiated from other encephalopathies of obscure origin as previously defined by Lyon et al. The active phase was dominated by coma or confusion and by abnormal movements, including disordered gesticulation and attacks of orofacial dyskinesia or limb dystonia associated with permanent rigidity and culminating in opisthotonic posturing. Repeated seizures were observed in only two patients. Permanent slow waves were recorded on the electroencephalogram in all patients, even during bursts of abnormal movements. Cerebrospinal fluid and results of serologic studies were normal throughout the course of the disease, and attempts at viral isolation and antiviral antibody detection yielded negative results. Brain imaging either showed no abnormalities or suggested a moderate degree of brain edema. The recovery phase, which extended for several weeks, was characterized by a rapid return of motor function and persistent behavioral and cognitive disturbances. Nonverbal reasoning recovered long before verbal expression returned to normal. Four patients eventually recovered fully, whereas two had mild sequelae. CorrectionThe Journal of PediatricsVol. 122Issue 3Preview Full-Text PDF" @default.
• W1979969283 created "2016-06-24" @default.
• W1979969283 creator A5006275997 @default.
• W1979969283 creator A5022291187 @default.
• W1979969283 creator A5022549487 @default.
• W1979969283 creator A5027798651 @default.
• W1979969283 creator A5057194886 @default.
• W1979969283 creator A5072319537 @default.
• W1979969283 date "1992-12-01" @default.
• W1979969283 modified "2023-10-18" @default.
• W1979969283 title "Coma associated with intense bursts of abnormal movements and long-lasting cognitive disturbances: An acute encephalopathy of obscure origin" @default.
• W1979969283 cites W1540872379 @default.
• W1979969283 cites W1973764649 @default.
• W1979969283 cites W1989577029 @default.
• W1979969283 cites W1993816176 @default.
• W1979969283 cites W2014395266 @default.
• W1979969283 cites W2017708875 @default.
• W1979969283 cites W2018676991 @default.
• W1979969283 cites W2021672876 @default.
• W1979969283 cites W2030865707 @default.
• W1979969283 cites W2041298357 @default.
• W1979969283 cites W2067767106 @default.
• W1979969283 cites W2070558008 @default.
• W1979969283 cites W2088998017 @default.
• W1979969283 cites W2105737988 @default.
• W1979969283 cites W2126238897 @default.
• W1979969283 cites W2129054062 @default.
• W1979969283 cites W2133371495 @default.
• W1979969283 cites W2147712133 @default.
• W1979969283 cites W2314473969 @default.
• W1979969283 cites W2326253968 @default.
• W1979969283 doi "https://doi.org/10.1016/s0022-3476(05)80326-9" @default.
• W1979969283 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1447643" @default.
• W1979969283 hasPublicationYear "1992" @default.
• W1979969283 type Work @default.
• W1979969283 sameAs 1979969283 @default.
• W1979969283 citedByCount "31" @default.
• W1979969283 countsByYear W19799692832012 @default.
• W1979969283 countsByYear W19799692832013 @default.
• W1979969283 countsByYear W19799692832014 @default.
• W1979969283 countsByYear W19799692832017 @default.
• W1979969283 countsByYear W19799692832018 @default.
• W1979969283 countsByYear W19799692832021 @default.
• W1979969283 countsByYear W19799692832022 @default.
• W1979969283 crossrefType "journal-article" @default.
• W1979969283 hasAuthorship W1979969283A5006275997 @default.
• W1979969283 hasAuthorship W1979969283A5022291187 @default.
• W1979969283 hasAuthorship W1979969283A5022549487 @default.
• W1979969283 hasAuthorship W1979969283A5027798651 @default.
• W1979969283 hasAuthorship W1979969283A5057194886 @default.
• W1979969283 hasAuthorship W1979969283A5072319537 @default.
• W1979969283 hasConcept C100136789 @default.
• W1979969283 hasConcept C118552586 @default.
• W1979969283 hasConcept C120665830 @default.
• W1979969283 hasConcept C121332964 @default.
• W1979969283 hasConcept C187212893 @default.
• W1979969283 hasConcept C2778559928 @default.
• W1979969283 hasConcept C2778621155 @default.
• W1979969283 hasConcept C42219234 @default.
• W1979969283 hasConcept C522805319 @default.
• W1979969283 hasConcept C71924100 @default.
• W1979969283 hasConceptScore W1979969283C100136789 @default.
• W1979969283 hasConceptScore W1979969283C118552586 @default.
• W1979969283 hasConceptScore W1979969283C120665830 @default.
• W1979969283 hasConceptScore W1979969283C121332964 @default.
• W1979969283 hasConceptScore W1979969283C187212893 @default.
• W1979969283 hasConceptScore W1979969283C2778559928 @default.
• W1979969283 hasConceptScore W1979969283C2778621155 @default.
• W1979969283 hasConceptScore W1979969283C42219234 @default.
• W1979969283 hasConceptScore W1979969283C522805319 @default.
• W1979969283 hasConceptScore W1979969283C71924100 @default.
• W1979969283 hasIssue "6" @default.
• W1979969283 hasLocation W19799692831 @default.
• W1979969283 hasLocation W19799692832 @default.
• W1979969283 hasOpenAccess W1979969283 @default.
• W1979969283 hasPrimaryLocation W19799692831 @default.
• W1979969283 hasRelatedWork W1963997438 @default.
• W1979969283 hasRelatedWork W1975409506 @default.
• W1979969283 hasRelatedWork W1993034175 @default.
• W1979969283 hasRelatedWork W206687392 @default.
• W1979969283 hasRelatedWork W2097534567 @default.
• W1979969283 hasRelatedWork W2505536857 @default.
• W1979969283 hasRelatedWork W2990799694 @default.
• W1979969283 hasRelatedWork W3198790571 @default.
• W1979969283 hasRelatedWork W3207786928 @default.
• W1979969283 hasRelatedWork W4231227970 @default.
• W1979969283 hasVolume "121" @default.
• W1979969283 isParatext "false" @default.
• W1979969283 isRetracted "false" @default.
• W1979969283 magId "1979969283" @default.
• W1979969283 workType "article" @default.