Matches in SemOpenAlex for { <https://semopenalex.org/work/W1979997643> ?p ?o ?g. }
- W1979997643 endingPage "445" @default.
- W1979997643 startingPage "437" @default.
- W1979997643 abstract "This study demonstrates the increased versatility of the Chiralcel® OJ-H stationary phase when using various alcohol/acetonitrile mobile phases. This chiral stationary phase has traditionally been employed in the normal phase mode and more recently with neat alcohols as eluents. Selected isomeric human mineralocorticoid receptor (hMR) antagonist pharmaceutical candidates and synthetic intermediates were separated using the Chiralcel® OJ-H HPLC column with novel polar cosolvent eluent systems. The capacity factors, resolution, and selectivity of the chiral separations were assessed while varying the alcohol/acetonitrile composition and alcohol identity. The mixed polar eluents provide separations that are nearly always superior to both the traditional hexane-rich and single-alcohol “polar organic” eluents for the compounds tested in this article. Chirality, 2006. © 2006 Wiley-Liss, Inc." @default.
- W1979997643 created "2016-06-24" @default.
- W1979997643 creator A5004823098 @default.
- W1979997643 creator A5013690731 @default.
- W1979997643 creator A5014477543 @default.
- W1979997643 creator A5033838699 @default.
- W1979997643 creator A5043542497 @default.
- W1979997643 creator A5077792062 @default.
- W1979997643 date "2006-01-01" @default.
- W1979997643 modified "2023-09-26" @default.
- W1979997643 title "Enantiomeric separation of mineralocorticoid receptor (hMR) antagonists using the Chiralcel® OJ-H HPLC column with novel polar cosolvent eluent systems" @default.
- W1979997643 cites W1565935315 @default.
- W1979997643 cites W1997748067 @default.
- W1979997643 cites W2001471596 @default.
- W1979997643 cites W2008463990 @default.
- W1979997643 cites W2009457961 @default.
- W1979997643 cites W2018272856 @default.
- W1979997643 cites W2024778670 @default.
- W1979997643 cites W2044931427 @default.
- W1979997643 cites W2048200495 @default.
- W1979997643 cites W2050741589 @default.
- W1979997643 cites W2074026046 @default.
- W1979997643 cites W2084500982 @default.
- W1979997643 cites W2093673306 @default.
- W1979997643 cites W2124524960 @default.
- W1979997643 cites W2129947301 @default.
- W1979997643 cites W2526994348 @default.
- W1979997643 cites W4232404445 @default.
- W1979997643 cites W1967070694 @default.
- W1979997643 doi "https://doi.org/10.1002/chir.20269" @default.
- W1979997643 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16634131" @default.
- W1979997643 hasPublicationYear "2006" @default.
- W1979997643 type Work @default.
- W1979997643 sameAs 1979997643 @default.
- W1979997643 citedByCount "7" @default.
- W1979997643 countsByYear W19799976432012 @default.
- W1979997643 countsByYear W19799976432020 @default.
- W1979997643 countsByYear W19799976432021 @default.
- W1979997643 countsByYear W19799976432023 @default.
- W1979997643 crossrefType "journal-article" @default.
- W1979997643 hasAuthorship W1979997643A5004823098 @default.
- W1979997643 hasAuthorship W1979997643A5013690731 @default.
- W1979997643 hasAuthorship W1979997643A5014477543 @default.
- W1979997643 hasAuthorship W1979997643A5033838699 @default.
- W1979997643 hasAuthorship W1979997643A5043542497 @default.
- W1979997643 hasAuthorship W1979997643A5077792062 @default.
- W1979997643 hasConcept C121332964 @default.
- W1979997643 hasConcept C124668440 @default.
- W1979997643 hasConcept C1276947 @default.
- W1979997643 hasConcept C16838498 @default.
- W1979997643 hasConcept C178790620 @default.
- W1979997643 hasConcept C179998833 @default.
- W1979997643 hasConcept C185592680 @default.
- W1979997643 hasConcept C20621625 @default.
- W1979997643 hasConcept C2777077568 @default.
- W1979997643 hasConcept C2777463227 @default.
- W1979997643 hasConcept C2781066024 @default.
- W1979997643 hasConcept C29705727 @default.
- W1979997643 hasConcept C43617362 @default.
- W1979997643 hasConcept C486523 @default.
- W1979997643 hasConcept C51724486 @default.
- W1979997643 hasConcept C52703039 @default.
- W1979997643 hasConcept C62520636 @default.
- W1979997643 hasConcept C7602139 @default.
- W1979997643 hasConceptScore W1979997643C121332964 @default.
- W1979997643 hasConceptScore W1979997643C124668440 @default.
- W1979997643 hasConceptScore W1979997643C1276947 @default.
- W1979997643 hasConceptScore W1979997643C16838498 @default.
- W1979997643 hasConceptScore W1979997643C178790620 @default.
- W1979997643 hasConceptScore W1979997643C179998833 @default.
- W1979997643 hasConceptScore W1979997643C185592680 @default.
- W1979997643 hasConceptScore W1979997643C20621625 @default.
- W1979997643 hasConceptScore W1979997643C2777077568 @default.
- W1979997643 hasConceptScore W1979997643C2777463227 @default.
- W1979997643 hasConceptScore W1979997643C2781066024 @default.
- W1979997643 hasConceptScore W1979997643C29705727 @default.
- W1979997643 hasConceptScore W1979997643C43617362 @default.
- W1979997643 hasConceptScore W1979997643C486523 @default.
- W1979997643 hasConceptScore W1979997643C51724486 @default.
- W1979997643 hasConceptScore W1979997643C52703039 @default.
- W1979997643 hasConceptScore W1979997643C62520636 @default.
- W1979997643 hasConceptScore W1979997643C7602139 @default.
- W1979997643 hasIssue "6" @default.
- W1979997643 hasLocation W19799976431 @default.
- W1979997643 hasLocation W19799976432 @default.
- W1979997643 hasOpenAccess W1979997643 @default.
- W1979997643 hasPrimaryLocation W19799976431 @default.
- W1979997643 hasRelatedWork W1996538340 @default.
- W1979997643 hasRelatedWork W2001949288 @default.
- W1979997643 hasRelatedWork W2018967969 @default.
- W1979997643 hasRelatedWork W2021792606 @default.
- W1979997643 hasRelatedWork W2054423503 @default.
- W1979997643 hasRelatedWork W2079852636 @default.
- W1979997643 hasRelatedWork W2119552130 @default.
- W1979997643 hasRelatedWork W2166263961 @default.
- W1979997643 hasRelatedWork W2256031060 @default.
- W1979997643 hasRelatedWork W2372778717 @default.
- W1979997643 hasVolume "18" @default.