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• W1980004611 abstract "Phosphorylation of the P‐light chain of myosin might be involved in the regulation of cardiac contractility. Thus an enhanced phosphorylation level of the P‐light chain catalyzed by Ca 2+ ‐calmodulin‐dependent myosin light chain kinase (MLCK) increased significantly the Ca 2+ sensitivity of chemically skinned ventricular fibre bundles of the pig. This effect was reversible. Whereas force development at submaximal Ca 2+ concentration (pCa 5.5) increased by ~ 50% in the presence of MLCK, maximum tension achieved at maximum Ca 2+ ‐concentration (pCa 4.3) was not affected." @default.
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• W1980004611 date "1985-09-23" @default.
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• W1980004611 title "The influence of P-light chain phosphorylation by myosin light chain kinase on the calcium sensitivity of chemically skinned heart fibres" @default.
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• W1980004611 doi "https://doi.org/10.1016/0014-5793(85)81027-9" @default.
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