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- W1980041610 abstract "The stereoselective synthesis of 4-substituted androstenes (8β,14α)30 and 36 related to inhibitors of the enzyme aromatase and 5α-reductase has been achieved in a short-step sequence from sandaracopimaric acid. The synthetic strategy is the stereoselective construction of ring D, and the appropriate modification of the A-ring diterpene functionality to the enone system found in the aromatase inhibitors. A parallel sequence is developed to obtain the isomers (8α,14β)31 and 41." @default.
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- W1980041610 date "1995-01-01" @default.
- W1980041610 modified "2023-10-18" @default.
- W1980041610 title "Synthesis of 4-hydroxy-15-oxaandrost-4-en-3-one and other potential aromatase inhibitors from sandaracopimaric acid" @default.
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- W1980041610 doi "https://doi.org/10.1039/p19950000569" @default.
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