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- W1980093815 abstract "Long-term potentiation (LTP), intensively studied in the hippocampus as a possible mnemonic device, has begun to be studied in the neocortex. In this study the effects of varying tetanic stimulus parameters on LTP of field potentials recorded from layer II/III induced by white matter stimulation in the in vitro rat visual cortical slice were examined. Low intensity tetanus was more effective in producing LTP than high-intensity tetanus, although single pulses of very high intensity reliably resulted in LTP. LTP consistently occurred following 2 Hz-60 min, or 100 Hz-10 min tetanus; whereas, 10 min of 7 and 25 Hz tetanus usually resulted in long-lasting depression. Although no obvious rule related tetanus frequency and duration to the incidence of LTP, an inverted-U relationship was found between tetanus frequency and LTP magnitude." @default.
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- W1980093815 date "1989-03-01" @default.
- W1980093815 modified "2023-09-26" @default.
- W1980093815 title "Induction of LTP in rat primary visual cortex: tetanus parameters" @default.
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- W1980093815 doi "https://doi.org/10.1016/0006-8993(89)90797-x" @default.
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