FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1980102913> ?p ?o ?g. }

• W1980102913 endingPage "1134" @default.
• W1980102913 startingPage "1123" @default.
• W1980102913 abstract "In pigeons, asymmetric photic stimulation around hatch induces functional visual asymmetries that are accompanied by left-right differences in tectal cell sizes. Different aspects of light-dependent neuronal differentiation are known to be mediated by the brain-derived neurotrophic factor (BDNF). Therefore, we investigated by means of single or triple BDNF- or saline-injections into the right eye of dark-incubated pigeon hatchlings if ocular BDNF enrichment mimics the effects of biased visual input. As adults, the birds were tested in a grit-grain discrimination task to estimate the degree and direction of visual lateralization followed by a morphometric analysis of retinal and tectal cells. The grit-grain discrimination task demonstrated that triple BDNF-injections enhanced visuoperceptual and visuomotor functioning of the left eye system. Morphometric analysis showed bilateral cell-type dependent effects within the optic tectum. While single-BDNF injections increased cell body sizes of calbindin-positive efferent neurons, triple-injections decreased cell sizes of parvalbumin-positive cells. Moreover, single BDNF-injections increased retinal cell sizes within the contralateral eye. Analysis of BDNF-induced intracellular signaling demonstrated enhanced downstream Ras activation for at least 24 h within both tectal halves whereas activity changes within the contralateral retina could not be detected. This points to primarily tectal effects of ocular BDNF. In sum, exogenous BDNF modulates the differentiation of retinotectal circuitries and dose-dependently shifts lateralized visuomotor processing towards the noninjected side. Since these effects are opposite to embryonic light stimulation, it is unlikely that the impact of light onto asymmetry formation is mediated by retinal BDNF." @default.
• W1980102913 created "2016-06-24" @default.
• W1980102913 creator A5000142659 @default.
• W1980102913 creator A5016342124 @default.
• W1980102913 creator A5079177957 @default.
• W1980102913 creator A5027514994 @default.
• W1980102913 date "2008-01-01" @default.
• W1980102913 modified "2023-10-14" @default.
• W1980102913 title "Breaking the balance: Ocular BDNF-injections induce visual asymmetry in pigeons" @default.
• W1980102913 cites W1484895811 @default.
• W1980102913 cites W1946971400 @default.
• W1980102913 cites W1969283694 @default.
• W1980102913 cites W1976641023 @default.
• W1980102913 cites W1984985847 @default.
• W1980102913 cites W1986325330 @default.
• W1980102913 cites W1987589619 @default.
• W1980102913 cites W1992086678 @default.
• W1980102913 cites W1993765672 @default.
• W1980102913 cites W1995374378 @default.
• W1980102913 cites W1996283634 @default.
• W1980102913 cites W1996540280 @default.
• W1980102913 cites W1997169135 @default.
• W1980102913 cites W2006352348 @default.
• W1980102913 cites W2011971142 @default.
• W1980102913 cites W2013754288 @default.
• W1980102913 cites W2016682408 @default.
• W1980102913 cites W2034124800 @default.
• W1980102913 cites W2036153337 @default.
• W1980102913 cites W2039620246 @default.
• W1980102913 cites W2040719317 @default.
• W1980102913 cites W2048121291 @default.
• W1980102913 cites W2052874814 @default.
• W1980102913 cites W2057068818 @default.
• W1980102913 cites W2060344893 @default.
• W1980102913 cites W2064156488 @default.
• W1980102913 cites W2071087336 @default.
• W1980102913 cites W2072162136 @default.
• W1980102913 cites W2072351646 @default.
• W1980102913 cites W2072378189 @default.
• W1980102913 cites W2079474887 @default.
• W1980102913 cites W2080057762 @default.
• W1980102913 cites W2085298903 @default.
• W1980102913 cites W2089422985 @default.
• W1980102913 cites W2093169179 @default.
• W1980102913 cites W2105012597 @default.
• W1980102913 cites W2105590520 @default.
• W1980102913 cites W2112933076 @default.
• W1980102913 cites W2120799362 @default.
• W1980102913 cites W2128960139 @default.
• W1980102913 cites W2131842077 @default.
• W1980102913 cites W2133093591 @default.
• W1980102913 cites W2139565721 @default.
• W1980102913 cites W2140493425 @default.
• W1980102913 cites W2152334170 @default.
• W1980102913 cites W2154727263 @default.
• W1980102913 cites W2155591155 @default.
• W1980102913 cites W2158132233 @default.
• W1980102913 cites W2160001127 @default.
• W1980102913 cites W2264255990 @default.
• W1980102913 cites W2497798620 @default.
• W1980102913 cites W4210982910 @default.
• W1980102913 cites W4233776906 @default.
• W1980102913 cites W4322702927 @default.
• W1980102913 doi "https://doi.org/10.1002/dneu.20647" @default.
• W1980102913 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18506770" @default.
• W1980102913 hasPublicationYear "2008" @default.
• W1980102913 type Work @default.
• W1980102913 sameAs 1980102913 @default.
• W1980102913 citedByCount "12" @default.
• W1980102913 countsByYear W19801029132012 @default.
• W1980102913 countsByYear W19801029132014 @default.
• W1980102913 countsByYear W19801029132017 @default.
• W1980102913 countsByYear W19801029132019 @default.
• W1980102913 countsByYear W19801029132020 @default.
• W1980102913 countsByYear W19801029132021 @default.
• W1980102913 crossrefType "journal-article" @default.
• W1980102913 hasAuthorship W1980102913A5000142659 @default.
• W1980102913 hasAuthorship W1980102913A5016342124 @default.
• W1980102913 hasAuthorship W1980102913A5027514994 @default.
• W1980102913 hasAuthorship W1980102913A5079177957 @default.
• W1980102913 hasConcept C105702510 @default.
• W1980102913 hasConcept C160539049 @default.
• W1980102913 hasConcept C169760540 @default.
• W1980102913 hasConcept C170493617 @default.
• W1980102913 hasConcept C24998067 @default.
• W1980102913 hasConcept C2777093970 @default.
• W1980102913 hasConcept C2778790584 @default.
• W1980102913 hasConcept C2779480072 @default.
• W1980102913 hasConcept C2780827179 @default.
• W1980102913 hasConcept C529278444 @default.
• W1980102913 hasConcept C552161191 @default.
• W1980102913 hasConcept C55493867 @default.
• W1980102913 hasConcept C86803240 @default.
• W1980102913 hasConceptScore W1980102913C105702510 @default.
• W1980102913 hasConceptScore W1980102913C160539049 @default.
• W1980102913 hasConceptScore W1980102913C169760540 @default.
• W1980102913 hasConceptScore W1980102913C170493617 @default.
• W1980102913 hasConceptScore W1980102913C24998067 @default.

• next