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- W1980147994 abstract "14 fungicides have been tested for genetic activity on diploid cells of the ascomycete Saccharomyces cerevisiae. The test system used was induction of: (1) mistotic gene conversion at 2 different loci; and (2) cytoplasmic respiratory-deficient mutants. 2 fungicides turned out to be strongly active in inducing mitotic gene conversion when applied as commercial preparations: Ortho-phaltan (N-(trichloromethylthio)phthalimide) and Polyram-combi (ammonia complex of zinc ethylenebis-(dithiocarbamate) and polyethylenebis(thiocarbamoyl)disulfide). Cignolin (1,8-dihydroxyanthranole), used in dermatology, did not induce mitotic gene conversion but induced cytoplasmic respiratory-deficient mutation at frequencies close to 100%. With 4 more fungicides only a week apparent induction of gene conversion could be observed: Antracol (zinc propylenebis(dithiocarbamate)), Basfungin (ammonia complex of zinc propylenebis (dithiocarbamate) and polypropylenebis(thiocarbamoyl)-disulfide), Dithane-Ultra (manganese-zinc ethylenebis(dithiocarbamate) complex) and Captan (N-(trichloromethylthio)-4-cyclohexene-1,2-dicarbaximide)." @default.
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- W1980147994 date "1970-12-01" @default.
- W1980147994 modified "2023-09-29" @default.
- W1980147994 title "Genetic effects of fungicides" @default.
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- W1980147994 doi "https://doi.org/10.1016/0027-5107(70)90081-3" @default.
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