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- W1980185092 abstract "In this study, we examined the effect of the 5-HT<sub>2A,C</sub> receptor agonist (±)-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) on locomotor activity and the head twitch response in rats by the repeated (twice daily for 4 days) subcutaneous administration of 0.9% saline (1 ml/kg) or (±)-3,4-Methylenedioxymethamphetamine (MDMA) (20 mg/kg), a compound that selectively destroys serotonergic nerve terminals. There was no difference between the MDMA- and saline-treated rats regarding the (±)-DOI-induced (0.625, 1.25 or 2.5 mg/kg, i.p.) increase and decrease in the head twitch response and horizontal locomotor activity, respectively. Overall, repeated MDMA does not alter the behavioral response of rats to (±)-DOI." @default.
- W1980185092 created "2016-06-24" @default.
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- W1980185092 date "1997-12-12" @default.
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- W1980185092 title "The Effect of the Repeated Administration of the Compound 3,4-Methylenedioxymethamphetamineon the Response of Rats to the5-HT<sub>2A,C</sub> Receptor Agonist (±)-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI)" @default.
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- W1980185092 doi "https://doi.org/10.1159/000026474" @default.
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