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- W1980187806 abstract "The levels of folate polyglutamate in red blood-cells in untreated pernicious anæmia were significantly lower than in controls. The level of free folate (glutamate chain length one to three) was unchanged. The data indicate that in vitamin-B12 deficiency there is a failure of synthesis of folate polyglutamate, the active coenzyme form. This leads to impaired entry of monoglutamate forms of folate into cells and an increase in plasma-folate. Consequent failure of folate coenzyme function leads to the well-known consequences of vitamin-B12 deficiency." @default.
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- W1980187806 date "1974-06-01" @default.
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- W1980187806 title "THE BIOCHEMICAL LESION IN VITAMIN-B12 DEFICIENCY IN MAN" @default.
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- W1980187806 doi "https://doi.org/10.1016/s0140-6736(74)90005-1" @default.
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