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• W1980206543 abstract "Objective To determine the possible role of prokineticin 2 in varicocele by inducing varicoceles in adult rats. Methods Forty male Sprague–Dawley rats were used for sham operation (n = 10) and varicocele (n = 30) groups. Experimental varicocele was induced by partial ligation of the left renal vein in the varicocele, whereas the sham operation group only received a sham induction of varicocele. Left testes were harvested for real-time quantitative polymerase chair readtion analysis 2, 4, and 8 weeks after the induction of varicocele. Results The expression of prokineticin 2 mRNA in 8-week varicocele-induced rats was significantly higher (P < .05) than that in the sham operation group. Conclusion The present study suggests that prokineticin 2 expression is increased by varicocele induction and it may have a role in varicocele-induced infertility. To determine the possible role of prokineticin 2 in varicocele by inducing varicoceles in adult rats. Forty male Sprague–Dawley rats were used for sham operation (n = 10) and varicocele (n = 30) groups. Experimental varicocele was induced by partial ligation of the left renal vein in the varicocele, whereas the sham operation group only received a sham induction of varicocele. Left testes were harvested for real-time quantitative polymerase chair readtion analysis 2, 4, and 8 weeks after the induction of varicocele. The expression of prokineticin 2 mRNA in 8-week varicocele-induced rats was significantly higher (P < .05) than that in the sham operation group. The present study suggests that prokineticin 2 expression is increased by varicocele induction and it may have a role in varicocele-induced infertility." @default.
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• W1980206543 date "2012-10-01" @default.
• W1980206543 modified "2023-09-25" @default.
• W1980206543 title "Potential Role of Prokineticin 2 in Experimental Varicocele-induced Rat Testes" @default.
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• W1980206543 doi "https://doi.org/10.1016/j.urology.2012.05.033" @default.
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