Matches in SemOpenAlex for { <https://semopenalex.org/work/W1980210147> ?p ?o ?g. }
Showing items 1 to 62 of
62
with 100 items per page.
- W1980210147 endingPage "352" @default.
- W1980210147 startingPage "351" @default.
- W1980210147 abstract "Mucins represent a largely untapped class of polymeric building block for biomaterials, therapeutics, and other biotechnology. Because the mucin polymer backbone is genetically encoded, sequence-specific mucins with defined physical and biochemical properties can be fabricated using recombinant technologies. The pendent O-glycans of mucins are increasingly implicated in immunomodulation, suppression of pathogen virulence, and other biochemical activities. Recent advances in engineered cell production systems are enabling the scalable synthesis of recombinant mucins with precisely tuned glycan side chains, offering exciting possibilities to tune the biological functionality of mucin-based products. New metabolic and chemoenzymatic strategies enable further tuning and functionalization of mucin O-glycans, opening new possibilities to expand the chemical diversity and functionality of mucin building blocks. In this review, we discuss these advances, and the opportunities for engineered mucins in biomedical applications ranging from in vitro models to therapeutics." @default.
- W1980210147 created "2016-06-24" @default.
- W1980210147 creator A5036899618 @default.
- W1980210147 date "2002-04-01" @default.
- W1980210147 modified "2023-10-18" @default.
- W1980210147 title "Protein sequencing and identification using tandem mass spectrometry. Edited by Michael Kinter, Nicholas E. Sherman, published by Wiley-Interscience Series on Mass Spectrometry, 2000, 301 p." @default.
- W1980210147 doi "https://doi.org/10.1016/s0300-9084(02)01395-0" @default.
- W1980210147 hasPublicationYear "2002" @default.
- W1980210147 type Work @default.
- W1980210147 sameAs 1980210147 @default.
- W1980210147 citedByCount "0" @default.
- W1980210147 crossrefType "journal-article" @default.
- W1980210147 hasAuthorship W1980210147A5036899618 @default.
- W1980210147 hasConcept C100631289 @default.
- W1980210147 hasConcept C104317684 @default.
- W1980210147 hasConcept C108625454 @default.
- W1980210147 hasConcept C171250308 @default.
- W1980210147 hasConcept C179264091 @default.
- W1980210147 hasConcept C181199279 @default.
- W1980210147 hasConcept C185592680 @default.
- W1980210147 hasConcept C192562407 @default.
- W1980210147 hasConcept C206212055 @default.
- W1980210147 hasConcept C40767141 @default.
- W1980210147 hasConcept C46111723 @default.
- W1980210147 hasConcept C55493867 @default.
- W1980210147 hasConcept C70721500 @default.
- W1980210147 hasConcept C86803240 @default.
- W1980210147 hasConceptScore W1980210147C100631289 @default.
- W1980210147 hasConceptScore W1980210147C104317684 @default.
- W1980210147 hasConceptScore W1980210147C108625454 @default.
- W1980210147 hasConceptScore W1980210147C171250308 @default.
- W1980210147 hasConceptScore W1980210147C179264091 @default.
- W1980210147 hasConceptScore W1980210147C181199279 @default.
- W1980210147 hasConceptScore W1980210147C185592680 @default.
- W1980210147 hasConceptScore W1980210147C192562407 @default.
- W1980210147 hasConceptScore W1980210147C206212055 @default.
- W1980210147 hasConceptScore W1980210147C40767141 @default.
- W1980210147 hasConceptScore W1980210147C46111723 @default.
- W1980210147 hasConceptScore W1980210147C55493867 @default.
- W1980210147 hasConceptScore W1980210147C70721500 @default.
- W1980210147 hasConceptScore W1980210147C86803240 @default.
- W1980210147 hasIssue "4" @default.
- W1980210147 hasLocation W19802101471 @default.
- W1980210147 hasOpenAccess W1980210147 @default.
- W1980210147 hasPrimaryLocation W19802101471 @default.
- W1980210147 hasRelatedWork W1693086232 @default.
- W1980210147 hasRelatedWork W197316820 @default.
- W1980210147 hasRelatedWork W1983588581 @default.
- W1980210147 hasRelatedWork W2005442970 @default.
- W1980210147 hasRelatedWork W2118002029 @default.
- W1980210147 hasRelatedWork W2171000759 @default.
- W1980210147 hasRelatedWork W2212665158 @default.
- W1980210147 hasRelatedWork W2606473534 @default.
- W1980210147 hasRelatedWork W4233442397 @default.
- W1980210147 hasRelatedWork W4311671429 @default.
- W1980210147 hasVolume "84" @default.
- W1980210147 isParatext "false" @default.
- W1980210147 isRetracted "false" @default.
- W1980210147 magId "1980210147" @default.
- W1980210147 workType "article" @default.