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- W1980265223 abstract "The effects of mercuric chloride and methylmercury chloride on the rat dorsal root ganglion neurons in primary culture were studied by the whole-cell patch clamp technique. gamma-Aminobutyric acid-induced chloride currents were augmented by mercuric chloride in a potent and efficacious manner; at concentrations of 1 and 10 microM, the current amplitude was increased to 130% and 200% of the control. Methylmercury even at 100 microM did not augment but rather decreased the GABA-induced chloride current. Both mercuric chloride and methylmercury generated slow inward currents by themselves. These currents are not mediated by the GABA-activated chloride channels or by voltage-activated sodium, potassium or calcium channels, and are likely to be due to non-specific cation channels." @default.
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- W1980265223 date "1991-06-01" @default.
- W1980265223 modified "2023-10-09" @default.
- W1980265223 title "Mercury modulation of GABA-activated chloride channels and non-specific cation channels in rat dorsal root ganglion neurons" @default.
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- W1980265223 doi "https://doi.org/10.1016/0006-8993(91)90913-g" @default.
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