Matches in SemOpenAlex for { <https://semopenalex.org/work/W1980310147> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W1980310147 endingPage "446" @default.
- W1980310147 startingPage "444" @default.
- W1980310147 abstract "In a double-blind study, the effect of high doses of methylprednisolone on the cerebral edema induced by cerebral infarction was evaluated in 76 Mongolian gerbils. The incidence of experimentally induced cerebral infarction following carotid artery ligation is high in these animals because they lack a posterior communicating artery. One hour after the left common carotid artery had been ligated, 34 animals were given 30 mg per kilogram of the adrenocorticosteroid and the dose was repeated 24 and 48 hours later. Thirty-four animals were given normal saline on the same treatment schedule. Eight animals with sham operations were not treated. The animals were observed for ten days for signs of stroke. Surviving animals were killed on the tenth day and all brains were examined macroscopically and microscopically. Stroke developed in 41% of all animals; 31% died within ten days. Of the steroid-treated animals, stroke developed in 38% and 26% died. Of the saline-treated animals, stroke developed in 44% and 35.5% died. The differences were not significant by chi square analysis and the authors concluded that large doses of methylprednisolone given one hour after carotid ligation failed to prevent or influence the course of experimental stroke." @default.
- W1980310147 created "2016-06-24" @default.
- W1980310147 creator A5062355291 @default.
- W1980310147 creator A5077227647 @default.
- W1980310147 creator A5088310138 @default.
- W1980310147 date "1974-07-01" @default.
- W1980310147 modified "2023-09-27" @default.
- W1980310147 title "Effect of Methylprednisolone on Experimental Cerebral Infarction in the Mongolian Gerbil" @default.
- W1980310147 cites W2016967697 @default.
- W1980310147 cites W2028405415 @default.
- W1980310147 cites W2038909506 @default.
- W1980310147 cites W2071697425 @default.
- W1980310147 cites W2110325718 @default.
- W1980310147 cites W2126654215 @default.
- W1980310147 cites W2319511828 @default.
- W1980310147 cites W2413709222 @default.
- W1980310147 cites W2418114904 @default.
- W1980310147 cites W2783212811 @default.
- W1980310147 doi "https://doi.org/10.1161/01.str.5.4.444" @default.
- W1980310147 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/4851666" @default.
- W1980310147 hasPublicationYear "1974" @default.
- W1980310147 type Work @default.
- W1980310147 sameAs 1980310147 @default.
- W1980310147 citedByCount "13" @default.
- W1980310147 countsByYear W19803101472012 @default.
- W1980310147 countsByYear W19803101472020 @default.
- W1980310147 crossrefType "journal-article" @default.
- W1980310147 hasAuthorship W1980310147A5062355291 @default.
- W1980310147 hasAuthorship W1980310147A5077227647 @default.
- W1980310147 hasAuthorship W1980310147A5088310138 @default.
- W1980310147 hasBestOaLocation W19803101471 @default.
- W1980310147 hasConcept C126322002 @default.
- W1980310147 hasConcept C127413603 @default.
- W1980310147 hasConcept C141071460 @default.
- W1980310147 hasConcept C179437574 @default.
- W1980310147 hasConcept C2777397205 @default.
- W1980310147 hasConcept C2777798775 @default.
- W1980310147 hasConcept C2779450755 @default.
- W1980310147 hasConcept C2780222073 @default.
- W1980310147 hasConcept C2780372218 @default.
- W1980310147 hasConcept C2780645631 @default.
- W1980310147 hasConcept C2780886150 @default.
- W1980310147 hasConcept C2781064879 @default.
- W1980310147 hasConcept C2987047532 @default.
- W1980310147 hasConcept C42219234 @default.
- W1980310147 hasConcept C500558357 @default.
- W1980310147 hasConcept C541997718 @default.
- W1980310147 hasConcept C71924100 @default.
- W1980310147 hasConcept C78519656 @default.
- W1980310147 hasConceptScore W1980310147C126322002 @default.
- W1980310147 hasConceptScore W1980310147C127413603 @default.
- W1980310147 hasConceptScore W1980310147C141071460 @default.
- W1980310147 hasConceptScore W1980310147C179437574 @default.
- W1980310147 hasConceptScore W1980310147C2777397205 @default.
- W1980310147 hasConceptScore W1980310147C2777798775 @default.
- W1980310147 hasConceptScore W1980310147C2779450755 @default.
- W1980310147 hasConceptScore W1980310147C2780222073 @default.
- W1980310147 hasConceptScore W1980310147C2780372218 @default.
- W1980310147 hasConceptScore W1980310147C2780645631 @default.
- W1980310147 hasConceptScore W1980310147C2780886150 @default.
- W1980310147 hasConceptScore W1980310147C2781064879 @default.
- W1980310147 hasConceptScore W1980310147C2987047532 @default.
- W1980310147 hasConceptScore W1980310147C42219234 @default.
- W1980310147 hasConceptScore W1980310147C500558357 @default.
- W1980310147 hasConceptScore W1980310147C541997718 @default.
- W1980310147 hasConceptScore W1980310147C71924100 @default.
- W1980310147 hasConceptScore W1980310147C78519656 @default.
- W1980310147 hasIssue "4" @default.
- W1980310147 hasLocation W19803101471 @default.
- W1980310147 hasLocation W19803101472 @default.
- W1980310147 hasOpenAccess W1980310147 @default.
- W1980310147 hasPrimaryLocation W19803101471 @default.
- W1980310147 hasRelatedWork W156408727 @default.
- W1980310147 hasRelatedWork W173759419 @default.
- W1980310147 hasRelatedWork W1980310147 @default.
- W1980310147 hasRelatedWork W2110325718 @default.
- W1980310147 hasRelatedWork W2147183676 @default.
- W1980310147 hasRelatedWork W2372289432 @default.
- W1980310147 hasRelatedWork W2413124689 @default.
- W1980310147 hasRelatedWork W2417569943 @default.
- W1980310147 hasRelatedWork W2437377785 @default.
- W1980310147 hasRelatedWork W2444182836 @default.
- W1980310147 hasVolume "5" @default.
- W1980310147 isParatext "false" @default.
- W1980310147 isRetracted "false" @default.
- W1980310147 magId "1980310147" @default.
- W1980310147 workType "article" @default.