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• W1980365673 endingPage "426" @default.
• W1980365673 startingPage "417" @default.
• W1980365673 abstract "Transposable Elements are pieces of DNA able to mobilize from one location to another within genomes. Although they constitute more than 50% of the human genome, they have been classified as selfish DNA, with the only mission to spread within genomes and generate more copies of themselves that will ensure their presence over generations. Despite their remarkable prevalence, only a minor group of transposable elements remain active in the human genome and can sporadically be associated with the generation of a genetic disorder due to their ongoing mobility. Most of the transposable elements identified in the human genome corresponded to fixed insertions that no longer move in genomes. As selfish DNA, transposable element insertions accumulate in cell types where genetic information can be passed to the next generation. Indeed, work from different laboratories has demonstrated that the main heritable load of TE accumulation in humans occurs during early embryogenesis. Thus, active transposable elements have a clear impact on our pluripotent genome. However, recent findings suggest that the main proportion of fixed non-mobile transposable elements might also have emerging roles in cellular plasticity. In this concise review, we provide an overview of the impact of currently active transposable elements in our pluripotent genome and further discuss new roles of transposable elements (active or not) in regulating pluripotency. This article is part of a Special Issue entitled: Stress as a fundamental theme in cell plasticity." @default.
• W1980365673 created "2016-06-24" @default.
• W1980365673 creator A5019524405 @default.
• W1980365673 creator A5027468756 @default.
• W1980365673 creator A5058223359 @default.
• W1980365673 date "2015-04-01" @default.
• W1980365673 modified "2023-10-15" @default.
• W1980365673 title "Retrotransposons in pluripotent cells: Impact and new roles in cellular plasticity" @default.
• W1980365673 cites W1220197623 @default.
• W1980365673 cites W1536915394 @default.
• W1980365673 cites W1964268598 @default.
• W1980365673 cites W1965141089 @default.
• W1980365673 cites W1966442169 @default.
• W1980365673 cites W1967722565 @default.
• W1980365673 cites W1974134624 @default.
• W1980365673 cites W1976342457 @default.
• W1980365673 cites W1978325079 @default.
• W1980365673 cites W1978353478 @default.
• W1980365673 cites W1980126223 @default.
• W1980365673 cites W1980487637 @default.
• W1980365673 cites W1981915622 @default.
• W1980365673 cites W1986319478 @default.
• W1980365673 cites W1988495745 @default.
• W1980365673 cites W1990015734 @default.
• W1980365673 cites W1990654003 @default.
• W1980365673 cites W1991333931 @default.
• W1980365673 cites W2007589425 @default.
• W1980365673 cites W2009503462 @default.
• W1980365673 cites W2011861577 @default.
• W1980365673 cites W2011927108 @default.
• W1980365673 cites W2015734897 @default.
• W1980365673 cites W2018177575 @default.
• W1980365673 cites W2029868997 @default.
• W1980365673 cites W2032679533 @default.
• W1980365673 cites W2035120673 @default.
• W1980365673 cites W2035260243 @default.
• W1980365673 cites W2036300762 @default.
• W1980365673 cites W2036994672 @default.
• W1980365673 cites W2037794677 @default.
• W1980365673 cites W2040741651 @default.
• W1980365673 cites W2041534255 @default.
• W1980365673 cites W2045807857 @default.
• W1980365673 cites W2046318418 @default.
• W1980365673 cites W2046415390 @default.
• W1980365673 cites W2046750712 @default.
• W1980365673 cites W2047285578 @default.
• W1980365673 cites W2047333953 @default.
• W1980365673 cites W2050557699 @default.
• W1980365673 cites W2051275283 @default.
• W1980365673 cites W2052608752 @default.
• W1980365673 cites W2054020326 @default.
• W1980365673 cites W2054890113 @default.
• W1980365673 cites W2055058281 @default.
• W1980365673 cites W2059083852 @default.
• W1980365673 cites W2061569670 @default.
• W1980365673 cites W2062238129 @default.
• W1980365673 cites W2062250400 @default.
• W1980365673 cites W2063669037 @default.
• W1980365673 cites W2064629259 @default.
• W1980365673 cites W2067343798 @default.
• W1980365673 cites W2068584800 @default.
• W1980365673 cites W2070807615 @default.
• W1980365673 cites W2073587729 @default.
• W1980365673 cites W2075168304 @default.
• W1980365673 cites W2075224242 @default.
• W1980365673 cites W2076945600 @default.
• W1980365673 cites W2077053535 @default.
• W1980365673 cites W2078418147 @default.
• W1980365673 cites W2080056745 @default.
• W1980365673 cites W2080173875 @default.
• W1980365673 cites W2085154635 @default.
• W1980365673 cites W2086739233 @default.
• W1980365673 cites W2086943348 @default.
• W1980365673 cites W2087056550 @default.
• W1980365673 cites W2087316628 @default.
• W1980365673 cites W2087377443 @default.
• W1980365673 cites W2089471275 @default.
• W1980365673 cites W2091279754 @default.
• W1980365673 cites W2091479795 @default.
• W1980365673 cites W2094913043 @default.
• W1980365673 cites W2096783891 @default.
• W1980365673 cites W2098474039 @default.
• W1980365673 cites W2098666676 @default.
• W1980365673 cites W2099468911 @default.
• W1980365673 cites W2100361299 @default.
• W1980365673 cites W2102773855 @default.
• W1980365673 cites W2107454957 @default.
• W1980365673 cites W2107950128 @default.
• W1980365673 cites W2111582716 @default.
• W1980365673 cites W2111957809 @default.
• W1980365673 cites W2113973815 @default.
• W1980365673 cites W2114766453 @default.
• W1980365673 cites W2114924552 @default.
• W1980365673 cites W2115759508 @default.
• W1980365673 cites W2119390857 @default.
• W1980365673 cites W2119742125 @default.
• W1980365673 cites W2120034162 @default.
• W1980365673 cites W2120762351 @default.

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