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• W1980370496 abstract "Probiotic strain Lactobacillus sporogenes and Bifidobacteria bifidum were used to assess the anti-inflammatory properties in Carrageenan induced acute inflammatory model. Non-encapsulated and encapsulated Probiotic strain of Bifidobacteria bifidum and Lactobacillus sporogenes was given orally. Diclofenac sodium was used as standard drug at a concentration of 150 mg/kg of body weight. Edema was induced with 1% carrageenan to all the groups except group A after half an hour of the oral treatments. Paw thickness was checked at t = 1, 2, 4 and 24 h. Stair climbing score and motility score were assessed at t = 24 h. Non-encapsulated and encapsulated Probiotic Bifidobacteria and Lactobacillus showed a statistically significant decrease in paw thickness at P < 0.05. The percentage inhibition in paw thickness of non-encapsulated and encapsulated probiotic L. sporogenes and B. bifidum is 37 ± 3% and 43 ± 2% after 24 h of treatment. They both significantly increased stair climbing and motility score. Probiotic B. bifidum and L. sporogenes significantly decreased the inflammatory reactions induced by carrageenan." @default.
• W1980370496 created "2016-06-24" @default.
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• W1980370496 date "2015-01-01" @default.
• W1980370496 modified "2023-10-12" @default.
• W1980370496 title "Evaluation of anti-inflammatory activity of probiotic on carrageenan-induced paw edema in Wistar rats" @default.
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• W1980370496 doi "https://doi.org/10.1016/j.ijbiomac.2014.09.059" @default.
• W1980370496 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25316426" @default.
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