FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1980419942> ?p ?o ?g. }

• W1980419942 endingPage "15518" @default.
• W1980419942 startingPage "15516" @default.
• W1980419942 abstract "The de novo design of membrane proteins remains difficult despite recent advances in understanding the factors that drive membrane protein folding and association. We have designed a membrane protein PRIME (PoRphyrins In MEmbrane) that positions two non-natural iron diphenylporphyrins (FeIIIDPP’s) sufficiently close to provide a multicentered pathway for transmembrane electron transfer. Computational methods previously used for the design of multiporphyrin water-soluble helical proteins were extended to this membrane target. Four helices were arranged in a D2-symmetrical bundle to bind two Fe(II/III) diphenylporphyrins in a bis-His geometry further stabilized by second-shell hydrogen bonds. UV−vis absorbance, CD spectroscopy, analytical ultracentrifugation, redox potentiometry, and EPR demonstrate that PRIME binds the cofactor with high affinity and specificity in the expected geometry." @default.
• W1980419942 created "2016-06-24" @default.
• W1980419942 creator A5006662454 @default.
• W1980419942 creator A5007172461 @default.
• W1980419942 creator A5011602419 @default.
• W1980419942 creator A5021623971 @default.
• W1980419942 creator A5044264604 @default.
• W1980419942 creator A5052866691 @default.
• W1980419942 creator A5069045760 @default.
• W1980419942 creator A5079347887 @default.
• W1980419942 creator A5089647566 @default.
• W1980419942 date "2010-10-14" @default.
• W1980419942 modified "2023-10-18" @default.
• W1980419942 title "De Novo Design and Molecular Assembly of a Transmembrane Diporphyrin-Binding Protein Complex" @default.
• W1980419942 cites W1969660397 @default.
• W1980419942 cites W1978101210 @default.
• W1980419942 cites W1980032355 @default.
• W1980419942 cites W1982764355 @default.
• W1980419942 cites W1987696643 @default.
• W1980419942 cites W1996202779 @default.
• W1980419942 cites W1999718832 @default.
• W1980419942 cites W2016140160 @default.
• W1980419942 cites W2016955847 @default.
• W1980419942 cites W2031320052 @default.
• W1980419942 cites W2034971743 @default.
• W1980419942 cites W2045942493 @default.
• W1980419942 cites W2047116104 @default.
• W1980419942 cites W2048840874 @default.
• W1980419942 cites W2064872769 @default.
• W1980419942 cites W2069280778 @default.
• W1980419942 cites W2073186943 @default.
• W1980419942 cites W2073275267 @default.
• W1980419942 cites W2075945436 @default.
• W1980419942 cites W2076444761 @default.
• W1980419942 cites W2078398728 @default.
• W1980419942 cites W2082260955 @default.
• W1980419942 cites W2144140949 @default.
• W1980419942 cites W2952831323 @default.
• W1980419942 doi "https://doi.org/10.1021/ja107487b" @default.
• W1980419942 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3016712" @default.
• W1980419942 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20945900" @default.
• W1980419942 hasPublicationYear "2010" @default.
• W1980419942 type Work @default.
• W1980419942 sameAs 1980419942 @default.
• W1980419942 citedByCount "106" @default.
• W1980419942 countsByYear W19804199422012 @default.
• W1980419942 countsByYear W19804199422013 @default.
• W1980419942 countsByYear W19804199422014 @default.
• W1980419942 countsByYear W19804199422015 @default.
• W1980419942 countsByYear W19804199422016 @default.
• W1980419942 countsByYear W19804199422017 @default.
• W1980419942 countsByYear W19804199422018 @default.
• W1980419942 countsByYear W19804199422019 @default.
• W1980419942 countsByYear W19804199422020 @default.
• W1980419942 countsByYear W19804199422021 @default.
• W1980419942 countsByYear W19804199422022 @default.
• W1980419942 countsByYear W19804199422023 @default.
• W1980419942 crossrefType "journal-article" @default.
• W1980419942 hasAuthorship W1980419942A5006662454 @default.
• W1980419942 hasAuthorship W1980419942A5007172461 @default.
• W1980419942 hasAuthorship W1980419942A5011602419 @default.
• W1980419942 hasAuthorship W1980419942A5021623971 @default.
• W1980419942 hasAuthorship W1980419942A5044264604 @default.
• W1980419942 hasAuthorship W1980419942A5052866691 @default.
• W1980419942 hasAuthorship W1980419942A5069045760 @default.
• W1980419942 hasAuthorship W1980419942A5079347887 @default.
• W1980419942 hasAuthorship W1980419942A5089647566 @default.
• W1980419942 hasBestOaLocation W19804199422 @default.
• W1980419942 hasConcept C112887158 @default.
• W1980419942 hasConcept C119599485 @default.
• W1980419942 hasConcept C123669783 @default.
• W1980419942 hasConcept C12554922 @default.
• W1980419942 hasConcept C127413603 @default.
• W1980419942 hasConcept C144647389 @default.
• W1980419942 hasConcept C152769699 @default.
• W1980419942 hasConcept C170493617 @default.
• W1980419942 hasConcept C178790620 @default.
• W1980419942 hasConcept C181199279 @default.
• W1980419942 hasConcept C185592680 @default.
• W1980419942 hasConcept C197957613 @default.
• W1980419942 hasConcept C203087120 @default.
• W1980419942 hasConcept C24530287 @default.
• W1980419942 hasConcept C2776545253 @default.
• W1980419942 hasConcept C32909587 @default.
• W1980419942 hasConcept C41625074 @default.
• W1980419942 hasConcept C47701112 @default.
• W1980419942 hasConcept C55493867 @default.
• W1980419942 hasConcept C71240020 @default.
• W1980419942 hasConcept C75473681 @default.
• W1980419942 hasConcept C8010536 @default.
• W1980419942 hasConcept C86803240 @default.
• W1980419942 hasConceptScore W1980419942C112887158 @default.
• W1980419942 hasConceptScore W1980419942C119599485 @default.
• W1980419942 hasConceptScore W1980419942C123669783 @default.
• W1980419942 hasConceptScore W1980419942C12554922 @default.
• W1980419942 hasConceptScore W1980419942C127413603 @default.
• W1980419942 hasConceptScore W1980419942C144647389 @default.
• W1980419942 hasConceptScore W1980419942C152769699 @default.

• next