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- W1980435940 abstract "In clinical trials, continuous monitoring is required when a large but nonsignificant test statistic is observed at an interim analysis. We consider a power family of continuous stopping boundaries that are optimal in the sense that they minimize the average stopping time for the given overall Type I error rate and power. The problem is formulated as a constrained optimization problem and is solved numerically using the differential evolution algorithm. The main results are the ready-to-use approximately optimal continuous stopping boundaries for a wide range of values of power and the most commonly used overall levels of significance." @default.
- W1980435940 created "2016-06-24" @default.
- W1980435940 creator A5066861955 @default.
- W1980435940 date "2009-10-28" @default.
- W1980435940 modified "2023-09-28" @default.
- W1980435940 title "Approximately Optimal Continuous Stopping Boundaries in a One-Sided Standard Sequential Test" @default.
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- W1980435940 doi "https://doi.org/10.1080/07474940903237963" @default.
- W1980435940 hasPublicationYear "2009" @default.
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